Analytical Data
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基因名
SEC14L2
- Application
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别名
Alpha tocopherol associated protein; Alpha-tocopherol-associated protein; C22orf6 ; hTAP; KIAA1186 ; KIAA1658 ; MGC65053 ; OTTHUMP00000198972; OTTHUMP00000198973; OTTHUMP00000198974; OTTHUMP00000199021; S14L2_HUMAN; SEC14 (S. cerevisiae) like 2; SEC14 like 2 (S. cerevisiae) ; SEC14 like protein 2; SEC14-like protein 2; Sec14l2; SPF; Squalene transfer protein; Supernatant protein factor; TAP; TAP1 ; tocopherol-associated protein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O76054
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表达区间
1-403 aa
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氨基酸序列
MSGRVGDLSP RQKEALAKFR ENVQDVLPAL PNPDDYFLLR WLRARSFDLQ KSEAMLRKHV EFRKQKDIDN IISWQPPEVI QQYLSGGMCG YDLDGCPVWY DIIGPLDAKG LLFSASKQDL LRTKMRECEL LLQECAHQTT KLGRKVETIT IIYDCEGLGL KHLWKPAVEA YGEFLCMFEE NYPETLKRLF VVKAPKLFPV AYNLIKPFLS EDTRKKIMVL GANWKEVLLK HISPDQVPVE YGGTMTDPDG NPKCKSKINY GGDIPRKYYV RDQVKQQYEH SVQISRGSSH QVEYEILFPG CVLRWQFMSD GADVGFGIFL KTKMGERQRA GEMTEVLPNQ RYNSHLVPED GTLTCSDPGI YVLRFDNTYS FIHAKKVNFT VEVLLPDKAS EEKMKQLGAG TPK
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分子量
46.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SEC14L2, a member of the SEC14 protein family, plays a crucial role in lipid metabolism and cellular signaling. It is primarily characterized by its phosphatidylinositol transfer activity, which facilitates the transport of lipids between membranes. Research into SEC14L2 has gained momentum due to its potential involvement in various physiological and pathological processes, including metabolic disorders, cancer, and neurodegeneration. Studies have shown that SEC14L2 is expressed in multiple tissues, with a significant impact on cellular functions such as growth, proliferation, and apoptosis. Given its role in lipid homeostasis, SEC14L2 is also implicated in the regulation of membrane trafficking, suggesting a broader relevance in cellular communication and metabolism. Investigating SEC14L2 and its protein interactions may provide insights into its mechanisms of action and its potential as a therapeutic target. With the growing recognition of the importance of lipid metabolism in health and disease, researchers are focusing on the functional characterization of SEC14L2, aiming to unravel its contributions to both normal physiology and the pathogenesis of various conditions. Overall, SEC14L2 represents a promising area of research that bridges fundamental biological processes with translational applications in medicine.
