Analytical Data
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基因名
CHCHD6
- Application
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别名
CHCHD6. CHCM1. MIC25
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BRQ6
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表达区间
1-235aa
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氨基酸序列
MGSTESSEGRRVSFGVDEEERVRVLQGVRLSENVVNRMKEPSSPPPAPTSSTFGLQDGNLRAPHKESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMESTIKPRRVEPVCSGLQAQILHCYRDRPHEVLLCSDLVKAYQRCVSAAHKG
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分子量
52.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CHCHD6, a member of the CHCHD (Coiled-Coil-Helix Domain Containing) family, has garnered significant attention in recent years due to its potential roles in mitochondrial function and cellular stress responses. This protein is characterized by the presence of coiled-coil and helix structures, which are crucial for its interaction with various molecular partners in the cell. Research indicates that CHCHD6 is involved in the regulation of apoptosis, oxidative stress, and mitochondrial dynamics, suggesting its importance in maintaining cellular homeostasis. Moreover, studies have linked CHCHD6 to several diseases, including neurodegenerative disorders, highlighting its role in pathways associated with cell survival and death. The recombinant expression of CHCHD6 allows for a deeper exploration of its structural and functional properties, facilitating the investigation of its interaction with other proteins and its implications in disease mechanisms. Understanding the biochemical characteristics and functional roles of CHCHD6 could pave the way for potential therapeutic strategies targeting mitochondrial dysfunction and related pathologies.
