Analytical Data
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基因名
RPS17
- Application
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别名
RPS17; RPS17L; 40S ribosomal protein S17; Small ribosomal subunit protein eS17
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P08708
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表达区间
2-135 aa
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氨基酸序列
GRVRTKTVK KAARVIIEKY YTRLGNDFHT NKRVCEEIAI IPSKKLRNKI AGYVTHLMKR IQRGPVRGIS IKLQEEERER RDNYVPEVSA LDQEIIEVDP DTKEMLKLLD FGSLSNLQVT QPTVGMNFKT PRGPV
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分子量
15.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RPS17, a gene encoding ribosomal protein S17, plays a crucial role in ribosome biogenesis and protein synthesis, essential processes for cellular growth and function. Notably, mutations in RPS17 have been associated with Diamond-Blackfan anemia, a rare inherited blood disorder characterized by macrocytic anemia and reduced erythroid progenitor cells. Research on recombinant RPS17 protein aims to elucidate its structural and functional properties, which are vital for understanding its role in ribosome assembly and cellular mechanisms. Advances in recombinant DNA technology enable the production of RPS17 in various expression systems, facilitating studies on protein interactions, folding, and its involvement in translational control. Additionally, the recombinant protein serves as a valuable tool in investigating the pathophysiology of related disorders, providing insights into therapeutic strategies. Through the characterization of recombinant RPS17, researchers hope to uncover the molecular basis of diseases linked to ribosomal protein deficiencies, ultimately contributing to the development of targeted therapies and improving patient outcomes.
