Analytical Data
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基因名
MCSFR
- Application
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别名
MCSFR；
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P07333
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表达区间
20-512aa
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氨基酸序列
IPVIEPSVPELVVKPGATVTLRCVGNGSVEWDGPPSPHWTLYSDGSSSIL STNNATFQNTGTYRCTEPGDPLGGSAAIHLYVKDPARPWNVLAQEVVVFE DQDALLPCLLTDPVLEAGVSLVRVRGRPLMRHTNYSFSPWHGFTIHRAKF IQSQDYQCSALMGGRKVMSISIRLKVQKVIPGPPALTLVPAELVRIRGEA AQIVCSASSVDVNFDVFLQHNNTKLAIPQQSDFHNNRYQKVLTLNLDQVD FQHAGNYSCVASNVQGKHSTSMFFRVVESAYLNLSSEQNLIQEVTVGEGL NLKVMVEAYPGLQGFNWTYLGPFSDHQPEPKLANATTKDTYRHTFTLSLP RLKPSEAGRYSFLARNPGGWRALTFELTLRYPPEVSVIWTFINGSGTLLC AASGYPQPNVTWLQCSGHTDRCDEAQVLQVWDDPYPEVLSQEPFHKVTVQ SLLTVETLEHNQTYECRAHNSVGSGSWAFIPISAGAHTHPPDE
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分子量
55 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MCSFR (Multi-Cytokine Signaling Fusion Receptor) is a recombinant protein that has emerged as a significant focus of study due to its potential role in modulating immune responses and its implications in various therapeutic applications. The background of MCSFR research is rooted in the increasing understanding of the complex interplay between cytokines and the immune system's functionality. Cytokines are critical signaling molecules that influence numerous physiological processes, including inflammation, cell proliferation, and differentiation. Dysregulation of cytokine signaling has been associated with a range of diseases, including autoimmune disorders and cancer. Therefore, developing a soluble receptor like MCSFR that can simultaneously bind to multiple cytokines presents an innovative approach to manipulating these pathways. This multi-targeting strategy allows for more efficient neutralization of pro-inflammatory cytokines, potentially leading to improved therapeutic outcomes. Additionally, research has highlighted the ability of MCSFR to enhance the specificity and efficacy of cytokine blockade, making it a promising candidate for clinical applications. The exploration of MCSFR not only represents a significant advancement in recombinant protein technology but also opens avenues for novel treatments in immunotherapy and beyond. Researchers are actively investigating the biochemical properties, functional mechanisms, and therapeutic potential of MCSFR to pave the way for its use in clinical settings, aiming to address unmet medical needs and improve patient care.
