Analytical Data
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Gene name
PA2G4
- Application
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Alternative Names
PA2G4；EBP1；Proliferation-associated Protein 2G4
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UQ80
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Expression Region
2-394aa
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AA Sequence
SGEDEQQEQ TIAEDLVVTK YKMGGDIANR VLRSLVEASS SGVSVLSLCE KGDAMIMEET GKIFKKEKEM KKGIAFPTSI SVNNCVCHFS PLKSDQDYIL KEGDLVKIDL GVHVDGFIAN VAHTFVVDVA QGTQVTGRKA DVIKAAHLCA EAALRLVKPG NQNTQVTEAW NKVAHSFNCT PIEGMLSHQL KQHVIDGEKT IIQNPTDQQK KDHEKAEFEV HEVYAVDVLV SSGEGKAKDA GQRTTIYKRD PSKQYGLKMK TSRAFFSEVE RRFDAMPFTL RAFEDEKKAR MGVVECAKHE LLQPFNVLYE KEGEFVAQFK FTVLLMPNGP MRITSGPFEP DLYKSEMEVQ DAELKALLQS SASRKTQKKK KKKASKTAEN ATSGETLEEN EAGD
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PA2G4, also known as proliferation-associated 2G4 or p15, is a protein that has gained interest in biomedical research due to its role in various cellular processes. Found predominantly in the nucleus, PA2G4 is involved in regulating cell proliferation, apoptosis, and transcription, suggesting its crucial role in maintaining cellular homeostasis. Dysregulation of PA2G4 has been implicated in several pathological conditions, including cancer, where its expression levels can correlate with tumor progression and patient prognosis. Research has shown that PA2G4 interacts with several key proteins, influencing pathways such as the cell cycle and growth factor signaling. Moreover, as a potential biomarker, PA2G4's expression may provide insights into tumor characteristics and therapeutic responses. Studies exploring the functional mechanisms of PA2G4 have revealed its involvement in the modulation of gene expression and potential interactions with oncogenic factors. Given these findings, the exploration of PA2G4 as a target for therapeutic interventions in cancer and other disorders continues to be of significant interest in molecular biology and clinical research. Understanding the nuances of PA2G4 function and its interplay with other cellular components could pave the way for novel strategies in disease management and treatment.
