Analytical Data
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基因名
PA2G4
- Application
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别名
PA2G4；EBP1；Proliferation-associated Protein 2G4
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UQ80
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表达区间
2-394aa
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氨基酸序列
SGEDEQQEQ TIAEDLVVTK YKMGGDIANR VLRSLVEASS SGVSVLSLCE KGDAMIMEET GKIFKKEKEM KKGIAFPTSI SVNNCVCHFS PLKSDQDYIL KEGDLVKIDL GVHVDGFIAN VAHTFVVDVA QGTQVTGRKA DVIKAAHLCA EAALRLVKPG NQNTQVTEAW NKVAHSFNCT PIEGMLSHQL KQHVIDGEKT IIQNPTDQQK KDHEKAEFEV HEVYAVDVLV SSGEGKAKDA GQRTTIYKRD PSKQYGLKMK TSRAFFSEVE RRFDAMPFTL RAFEDEKKAR MGVVECAKHE LLQPFNVLYE KEGEFVAQFK FTVLLMPNGP MRITSGPFEP DLYKSEMEVQ DAELKALLQS SASRKTQKKK KKKASKTAEN ATSGETLEEN EAGD
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PA2G4, also known as proliferation-associated 2G4 or p15, is a protein that has gained interest in biomedical research due to its role in various cellular processes. Found predominantly in the nucleus, PA2G4 is involved in regulating cell proliferation, apoptosis, and transcription, suggesting its crucial role in maintaining cellular homeostasis. Dysregulation of PA2G4 has been implicated in several pathological conditions, including cancer, where its expression levels can correlate with tumor progression and patient prognosis. Research has shown that PA2G4 interacts with several key proteins, influencing pathways such as the cell cycle and growth factor signaling. Moreover, as a potential biomarker, PA2G4's expression may provide insights into tumor characteristics and therapeutic responses. Studies exploring the functional mechanisms of PA2G4 have revealed its involvement in the modulation of gene expression and potential interactions with oncogenic factors. Given these findings, the exploration of PA2G4 as a target for therapeutic interventions in cancer and other disorders continues to be of significant interest in molecular biology and clinical research. Understanding the nuances of PA2G4 function and its interplay with other cellular components could pave the way for novel strategies in disease management and treatment.
