Analytical Data
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Gene name
Mcpt2
- Application
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Alternative Names
Mcpt2；Mast cell protease 2
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Species
Mouse
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P15119
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Expression Region
21-244aa
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AA Sequence
IIGGVEAKPH SRPYMAYLKF TTKNGSKERC GGFLIAPQFV MTAAHCNGSE ISVILGAHNI NKNEPTQQII KTEKTFVHPK FQYLSGFYDI MLLKLQKKAE LNSDVDVISL PSSSDFIKPG KMCWTAGWGK TGKNNPLSVT LREVELRIMD QEACKDHSDY DYQLQVCAGS PTTSKSIGQG DSGGPLVCDS VAHGIASSYE AKAPAVFTRI SYYLPWIYKV LKSK
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Molecular Weight
26.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Mcpt2, or mast cell protease 2, is a member of the serine protease family primarily expressed in mast cells, which are critical components of the immune system. This protease plays a vital role in various physiological and pathological processes, including inflammation, allergy, and defense against pathogens. The study of Mcpt2 particularly emphasizes its involvement in modulating immune responses, especially in allergic reactions and asthma. Research has indicated that Mcpt2 can influence the activation of other immune cells, release of cytokines, and degradation of extracellular matrix components, thereby affecting tissue remodeling and inflammation. As a result, understanding the mechanisms through which Mcpt2 operates could unveil novel therapeutic targets for allergic and inflammatory diseases. Recombining Mcpt2 protein for experimental purposes offers valuable insights into its functional properties, interactions with other molecules, and potential contributions to disease pathways. This has led to increasing interest among researchers in investigating its structure, activity, and regulation, highlighting its significance in mast cell biology and the broader context of immune system regulation.
