Analytical Data
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Gene name
CCDC65
- Application
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Alternative Names
CCDC65; DRC2Dynein regulatory complex subunit 2; Coiled-coil domain-containing Protein 65; Testis development Protein NYD-SP28
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8IXS2
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Expression Region
1-484aa
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AA Sequence
MPKKEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHRRAQLLDINGKLREMLKQYLDGISVSDEVLSQLNPLFIVNYQSNLLQPLSIRIAHPGDKQHPTT
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Molecular Weight
83.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CCDC65, known as Coiled-Coil Domain Containing 65, is a protein that has garnered attention in recent years due to its potential roles in various cellular processes and its implications in health and disease. Initially identified as a component in ciliary structures, CCDC65 is believed to be involved in the formation and maintenance of cilia, organelles critical for cellular signaling and movement. Disruptions in ciliary function have been linked to a range of disorders, collectively known as ciliopathies, which can affect organs and systems throughout the body. Furthermore, studies have indicated that CCDC65 may play a role in cellular signaling pathways, influencing processes such as cell migration, proliferation, and differentiation. The importance of CCDC65 in the context of disease, including its potential involvement in cancer and developmental disorders, has led to increased interest in its molecular mechanisms, structure, and interactions with other proteins. Thus, the characterization of CCDC65 as a recombinant protein is vital for elucidating its functional roles, facilitating drug development, and advancing our understanding of ciliary biology and associated pathologies. Researchers are actively exploring its biochemical properties and interactions, which could pave the way for novel therapeutic strategies targeting related diseases. The recombination and study of CCDC65 offer insights into fundamental biological processes and hold promise for future biotechnological applications.
