Analytical Data
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基因名
CCDC21
- Application
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别名
CCDC21; Centrosomal Protein of 85 kDa; CEP85; CEP85_HUMAN; Coiled-coil domain containing 21; Coiled-coil domain-containing Protein 21; DKFZp434L0117; DKFZp434P232; FLJ13976
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6P2H3
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表达区间
1-762aa
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氨基酸序列
MAMQEKYPTEGISHVTSPSSDVIQKGSSLGTEWQTPVISEPFRSRFSRCSSVADSGDTAIGTSCSDIAEDFCSSSGSPPFQPIKSHVTIPTAHVMPSTLGTSPAKPNSTPVGPSSSKLPLSGLAESVGMTRNGDLGAMKHSPGLSRDLMYFSGATGENGIEQSWFPAVGHERQEEARKFDIPSMESTLNQSAMMETLYSDPHHRVRFHNPRTSTSKELYRVLPEAKKAPGSGAVFERNGPHSNSSGVLPLGLQPAPGLSKPLPSQVWQPSPDTWHPREQSCELSTCRQQLELIRLQMEQMQLQNGAICHHPAAFGPSLPILEPAQWISILNSNEHLLKEKELLIDKQRKHISQLEQKVRESELQVHSALLGRPAPFGDVCLLRLQELQRENTFLRAQFAQKTEALSREKIDLEKKLSASEVEVQLIRESLKVALQKHSEEVKKQEERVKGRDKHINNLKKKCQKESEQNREKQQRIETLERYLADLPTLEDHQKQSQQLKDSELKSTELQEKVTELESLLEETQAICREKEIQLESLRQREAEFSSAGHSLQDKQSVEETSGEGPEVEMESWQKRYDSLQKIVEKQQQKMDQLRSQVQSLEQEVAQEEGTSQALREEAQRRDSALQQLRTAVKELSVQNQDLIEKNLTLQEHLRQAQPGSPPSPDTAQLALELHQELASCLQDLQAVCSIVTQRAQGHDPNLSLLLGIHSAQHPETQLDLQKPDVIKRKLEEVQQLRRDIEDLRTTMSDRYAQDMGENCVTQ
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分子量
112 KDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCDC21, or Coiled-Coil Domain Containing 21, is a protein that has garnered attention due to its potential roles in various cellular processes, particularly in cilia formation and function. Cilia are essential cellular organelles involved in signaling pathways and cellular movement, playing crucial roles in development and homeostasis. Dysfunction of ciliary proteins is linked to several diseases, including ciliopathies, which encompass a range of genetic disorders characterized by abnormal cilia structure or function. Understanding the structure and function of CCDC21 is vital for elucidating its role in cilium biology and its implications in health and disease. Recombinant CCDC21 protein has been produced to study its molecular interactions, structural properties, and biochemical functions. By investigating the physiological roles of CCDC21, researchers aim to uncover its contribution to ciliary signaling pathways and its involvement in disease mechanisms. This could potentially lead to the development of therapeutic strategies targeting CCDC21-related disorders. The ongoing research aims to clarify the functional mechanisms of CCDC21 and its interaction with other ciliary proteins, contributing to a deeper understanding of cilia-related diseases and advancing the field of cellular biology.
