Analytical Data
-
Gene name
CCDC124
- Application
-
Alternative Names
1810023B24Rik; CC124_HUMAN; CCDC124; Coiled coil domain containing 124; Coiled-coil domain-containing Protein 124; RGD1310931
-
Species
Human
-
Source
E. coli
-
Tag
GST-tag at N-terminal
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q96CT7
-
Expression Region
1-223aa
-
AA Sequence
MPKKFQGENT KSAAARARRA EAKAAADAKK QKELEDAYWK DDDKHVMRKE QRKEEKEKRR LDQLERKKET QRLLEEEDSK LKGGKAPRVA TSSKVTRAQI EDTLRRDHQL REAPDTAEKA KSHLEVPLEE NVNRRVLEEG SVEARTIEDA IAVLSVAEEA ADRHPERRMR AAFTAFEEAQ LPRLKQENPN MRLSQLKQLL KKEWLRSPDN PMNQRAVPFN APK
-
Molecular Weight
52.2 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CCDC124, a coiled-coil domain-containing protein, has garnered attention in recent years due to its potential role in various cellular processes and diseases. Research indicates that CCDC124 is involved in important biological functions such as cell division, DNA repair, and the regulation of the mitotic spindle. Dysregulation of this protein has been linked to various cancers, suggesting that it may play a crucial role in tumorigenesis. Furthermore, its coiled-coil structure may facilitate protein-protein interactions, which are essential for cellular signaling pathways and structural integrity. As scientists explore the mechanisms underlying these processes, the recombinant production of CCDC124 becomes vital for functional studies and therapeutic applications. Using recombinant DNA technology, researchers can produce this protein in controlled environments, allowing for detailed investigations into its structure and function. Understanding the biological significance of CCDC124 is not only crucial for basic research but also has implications for the development of novel cancer therapies. The study of this protein is a rapidly evolving field that promises insights into fundamental cellular mechanisms and potential interventions in cancer treatment.
