Analytical Data
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Gene name
CCDC114
- Application
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Alternative Names
CCDC114; Coiled-coil domain-containing Protein 114
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96M63
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Expression Region
1-670aa
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AA Sequence
MEGERRAYSK EVHQRINKQL EEIRRLEEVR GDLQVQISAA QNQVKRLRDS QRLENMDRLL KGRAQVQAEI EELQEQTRAL DKQIQEWETR IFTHSKNVRS PGFILDQKVK IRRRIRILEN QLDRVTCHFD NQLVRNAALR EELDLLRIDR NRYLNVDRKL KKEIHHLHHL VSTLILSSTS AYAVREEAKA KMGLLRERAE KEEAQSEMEA QVLQRQILHL EQLHHFLKLK NNDRQPDPDV LEKREKQAGE VAEGVWKTSQ ERLVLCYEDA LNKLSQLMGE SDPDLLVQKY LEIEERNFAE FNFINEQNLE LEHVQEEIKE MQEALVSARA SKDDQHLLQE QQQKVLQQRM DKVHSEAERL EARFQDVRGQ LEKLKADIQL LFTKAHCDSS MIDDLLGVKT SMGDRDMGLF LSLIEKRLVE LLTVQAFLHA QSFTSLADAA LLVLGQSLED LPKKMAPLQP PDTLEDPPGF EASDDYPMSR EELLSQVEKL VELQEQAEAQ RQKDLAAAAA KLDGTLSVDL ASTQRAGSST VLVPTRHPHA IPGSILSHKT SRDRGSLGHV TFGGLSSSTG HLPSHITHGD PNTGHVTFGS TSASSGGHVT FRPVSASSYL GSTGYVGSSR GGENTEGGVE SGGTASDSSG GLGSSRDHVS STGPASSTGP GSSTSKDSRG
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Molecular Weight
75 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CCDC114, or coiled-coil domain containing 114, is a protein that has garnered increasing attention in the field of molecular biology due to its potential roles in cellular processes and disease mechanisms. Initially identified as a coiled-coil protein, CCDC114 is believed to participate in various cellular functions, including protein-protein interactions, cellular signaling, and structural organization within the cell. The study of CCDC114 is particularly relevant in the context of its implications in specific diseases, such as cancer and genetic disorders. Recent research has highlighted its involvement in the mitotic process and its association with centrosomes, critical for proper cell division. Furthermore, mutations or dysregulation of CCDC114 have been linked to developmental abnormalities and various pathologies, underscoring the importance of understanding its functional mechanisms. Investigating the structure and function of CCDC114 not only contributes to our fundamental knowledge of cellular biology but also opens up potential therapeutic avenues for conditions arising from its malfunction. As research progresses, a more detailed characterization of CCDC114 at molecular and cellular levels is expected to yield insights that could enhance our understanding of its role in health and disease.
