Analytical Data
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Gene name
CARF
- Application
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Alternative Names
Amyotrophic lateral sclerosis 2 (juvenile) chromosome region candidate 8; Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 Protein; Calcium response factor
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8N187
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Expression Region
1-579aa
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AA Sequence
MAQEVSEYLSQNPRVAAWVEALRCDGETDKHWRHRRDFLLRNAGDLAPAGGAASASTDEAADAESGTRNRQLQQLISFSMAWANHVFLGCRYPQKVMDKILSMAEGIKVTDAPTYTTRDELVAKVKKRGISSSNEGVEEPSKKRVIEGKNSSAVEQDHAKTSAKTERASAQQENSSTCIGSAIKSESGNSARSSGISSQNSSTSDGDRSVSSQSSSSVSSQVTTAGSGKASEAEAPDKHGSSFVSLLKSSVNSHMTQSTDSRQQSGSPKKSALEGSSASASQSSSEIEVPLLGSSGSSEVELPLLSSKPSSETASSGLTSKTSSEASVSSSVAKNSSSSGTSLLTPKSSSSTNTSLLTSKSTSQVAASLLASKSSSQTSGSLVSKSTSLASVSQLASKSSSQTSTSQLPSKSTSQSSESSVKFSCKLTNEDVKQKQPFFNRLYKTVAWKLVAVGGFSPNVNHGELLNAAIEALKATLDVFFVPLKELADLPQNKSSQESIVCELRCKSVYLGTGCGKSKENAKAVASREALKLFLKKKVVVKICKRKYRGSEIEDLVLLDEESRPVNLPPALKHPQELL
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Molecular Weight
89.43 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CARF (CDTA-Associated RNA-binding Factor) is a key protein involved in various cellular processes, including RNA metabolism and gene regulation. Its role in stress responses and cellular homeostasis has garnered considerable attention in recent years. The need to understand CARF's function is driven by its potential implications in disease mechanisms, particularly in cancer and neurodegenerative disorders. Recent studies have indicated that CARF acts as an RNA-binding protein that modulates the stability and translation of specific mRNAs, thereby influencing cellular responses to environmental stresses. Researchers have been exploring CARF's structural characteristics, interaction networks, and regulatory pathways to elucidate its functional mechanisms. The potential of CARF as a therapeutic target or biomarker for various diseases remains a promising area for future investigations. Understanding CARF's molecular dynamics may provide insights into its contributions to pathophysiological processes and could lead to the development of innovative treatment strategies. As research progresses, CARF's role in modulating gene expression and its involvement in developmental processes continue to be areas of intense interest within the scientific community.
