Analytical Data
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Gene name
RBM9
- Application
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Alternative Names
RNA binding protein fox-1 homolog 2. Fox-1 homolog B. Hexaribonucleotide-binding protein 2. RNA-binding motif protein 9. RNA-binding protein 9. Repressor of tamoxifen transcriptional activity
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O43251
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Expression Region
1-450 aa
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AA Sequence
MAEGAQPQQPPQLGPGAAARGMKRESELELPVPGAGGDGADPGLSKRPRTEEAAADGGGGMQNEPLTPGYHGFPARDSQGNQEPTTTPDAMVQPFTTIPFPPPPQNGIPTEYGVPHTQDYAGQTGEHNLTLYGSTQAHGEQSSNSPSTQNGSLTTEGGAQTDGQQSQTQSSENSESKSTPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFENSADADRAREKLHGTVVEGRKIEVNNATARVMTNKKMVTPYANGWKLSPVVGAVYGPELYAAFSFQADVSLGNDAAVPLSGRGGINTYIPLISLPLVPGFPYPTAATTAAAFRGAHLRGRGRTVYGAVRAVPPTAIPAYPGVVYQDGFYGADLYGGYAACRYAQPATATAATAAAAAAAAYGDGYGRVYTADPYHALAPAASYGVGAVASLYRGGYSRFAPY
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Molecular Weight
73.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RBM9 (RNA-binding motif protein 9) is an emerging protein of interest in the field of molecular biology due to its critical role in RNA processing and regulation. Initial studies have linked RBM9 to essential cellular processes such as splicing, translation, and RNA stability, suggesting that it could play a vital role in gene expression. Furthermore, research has indicated that RBM9 may be involved in various pathophysiological conditions, including cancer, where its dysregulation could contribute to tumorigenesis and disease progression. Investigations into the structure and function of RBM9 have underscored its RNA-binding capabilities, prompting scientists to explore its interactions with a range of RNA substrates. The recombinant expression of RBM9 has enabled researchers to study its functional properties in detail, paving the way for elucidating its precise role within the cell. Understanding RBM9 at the molecular level could provide insights into its potential as a therapeutic target, particularly in diseases where RNA regulation is disrupted. Consequently, ongoing studies aim to define the mechanism by which RBM9 modulates RNA fate and its implications in health and disease, contributing to a broader comprehension of post-transcriptional regulation of gene expression.
