Analytical Data
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基因名
ACP5
- Application
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别名
ACP5；Tartrate-resistant acid phosphatase type 5
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P13686
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表达区间
22-325aa
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氨基酸序列
ATPALRFVAVGDWGGVPNAPFHTAREMANAKEIARTVQILGADFILSLGDNFYFTGVQDINDKRFQETFEDVFSDRSLRKVPWYVLAGNHDHLGNVSAQIAYSKISKRWNFPSPFYRLHFKIPQTNVSVAIFMLDTVTLCGNSDDFLSQQPERPRDVKLARTQLSWLKKQLAAAREDYVLVAGHYPVWSIAEHGPTHCLVKQLRPLLATYGVTAYLCGHDHNLQYLQDENGVGYVLSGAGNFMDPSKRHQRKVPNGYLRFHYGTEDSLGGFAYVEISSKEMTVTYIEASGKSLFKTRLPRRARP
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分子量
35.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ACP5, also known as acid phosphatase 5, is a member of the acid phosphatase family, which plays a vital role in regulating various physiological processes, including bone resorption, immune response, and cellular signaling. Research into ACP5 has gained significant attention due to its involvement in pathological conditions such as osteoporosis and certain types of cancers. As a secretory glycoprotein, ACP5 is primarily produced by osteoclasts and is crucial for the degradation of phosphate esters, thus contributing to the mineralization of bone. Understanding the molecular structure and functional mechanisms of ACP5 can provide insights into its regulatory roles and potential therapeutic targets. Advances in recombinant DNA technology have facilitated the production of recombinant ACP5, enabling detailed studies of its enzymatic activity, substrate specificity, and interaction with other biomolecules. This research not only enhances our understanding of ACP5's role in physiology and pathology but also opens avenues for the development of novel treatments aimed at diseases associated with ACP5 dysregulation. As such, the exploration of ACP5 as a therapeutic target has become an important focus in biomedical research, particularly in conditions where bone metabolism is disrupted.
