Analytical Data
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Gene name
UL130
- Application
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Alternative Names
UL130；VEGF165R2；Neuropilin-2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P16772
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Expression Region
26-214aa
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AA Sequence
SPWSTLTANQNPSPPWSKLTYSKPHDAATFYCPFLYPSPPRSPLQFSGFQQVSTGPECRNETLYLLYNREGQTLVERSSTWVKKVIWYLSGRNQTILQRMPQTASKPSDGNVQISVEDAKIFGAHMVPKQTKLLRFVVNDGTRYQMCVMKLESWAHVFRDYSVSFQVRLTFTEANNQTYTFCTHPNLIV
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Molecular Weight
37.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
UL130 is a protein encoded by the human cytomegalovirus (HCMV), a member of the herpesvirus family known for its ability to establish lifelong infections. The study of UL130 is particularly significant due to its role in viral pathogenesis and immune evasion. HCMV is a major cause of congenital infections and poses severe risks to immunocompromised individuals, such as organ transplant recipients and HIV patients. Research has shown that UL130 is involved in the modulation of the host immune response, particularly by influencing the activity of natural killer (NK) cells and T cells, which are crucial for controlling viral infections. Understanding the structure and function of UL130 can provide insights into the viral life cycle and its interactions with host immune mechanisms. Additionally, characterizing UL130 may aid in the development of novel antiviral therapies and vaccines. Recent studies have focused on the protein's interactions with host cell receptors and its potential role in promoting viral entry and replication. Overall, the investigation of UL130 not only enhances our understanding of HCMV biology but also highlights potential targets for therapeutic intervention in diseases associated with this ubiquitous virus.
