Analytical Data
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基因名
C21orf59
- Application
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别名
C21orf48; C21orf59; Chromosome 21 open reading frame 59; CILD26; CU059_HUMAN; FBB18; FLJ20467; FLJ37137; FLJ40247; Prostate cancer upregulated Protein 1; Uncharacterized Protein C21orf59
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P57076
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表达区间
1-290aa
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氨基酸序列
MVLLHVKRGDESQFLLQAPGSTELEELTVQVARVYNGRLKVQRLCSEMEELAEHGIFLPPNMQGLTDDQIEELKLKDEWGEKCVPSGGAVFKKDDIGRRNGQAPNEKMKQVLKKTIEEAKAIISKKQVEAGVCVTMEMVKDALDQLRGAVMIVYPMGLPPYDPIRMEFENKEDLSGTQAGLNVIKEAEAQLWWAAKELRRTKKLSDYVGKNEKTKIIAKIQQRGQGAPAREPIISSEEQKQLMLYYHRRQEELKRLEENDDDAYLNSPWADNTALKRHFHGVKDIKWRPR
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分子量
59.6 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
C21orf59, also known as "Chromosome 21 Open Reading Frame 59," has emerged as a significant protein in various biological studies, particularly in relation to cell growth and differentiation. Located on chromosome 21, it draws interest due to its potential implications in genetic disorders, including Down syndrome, where the overexpression of genes on this chromosome may contribute to the phenotypic traits observed in affected individuals. Recent research has focused on the recombinant expression of C21orf59 to better understand its functional role and interactions within cellular mechanisms. The availability of high-purity recombinant C21orf59 protein allows for in-depth analysis through biophysical and biochemical assays. These studies aim to elucidate its structure-function relationship, revealing how C21orf59 may participate in cellular pathways and influencing various diseases. Furthermore, understanding C21orf59’s role can provide insights into novel therapeutic targets for related genetic conditions. With advancements in recombinant DNA technology and protein purification methods, the investigation into C21orf59 is paving the way for significant breakthroughs in both basic research and potential clinical applications, highlighting the importance of this protein in the realm of molecular biology and genetics.
