Analytical Data
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基因名
RAB9B
- Application
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别名
RAB 9B; RAB 9L; Rab-9-like protein; Rab-9L; RAB9 like protein; Rab9b; RAB9B member RAS oncogene family; RAB9B_HUMAN; RAB9L; Ras related protein Rab9B; Ras-related protein Rab-9B
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NP90
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表达区间
1-201 aa
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氨基酸序列
MSGKSLLLKV ILLGDGGVGK SSLMNRYVTN KFDSQAFHTI GVEFLNRDLE VDGRFVTLQI WDTAGQERFK SLRTPFYRGA DCCLLTFSVD DRQSFENLGN WQKEFIYYAD VKDPEHFPFV VLGNKVDKED RQVTTEEAQT WCMENGDYPY LETSAKDDTN VTVAFEEAVR QVLAVEEQLE HCMLGHTIDL NSGSKAGSSC C
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分子量
22.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RAB9B is a member of the RAB family of small GTPases, which play crucial roles in intracellular trafficking and organelle dynamics. This particular protein is predominantly involved in the transport of membrane proteins from the endosome to the trans-Golgi network. Disruption of RAB9B function has been implicated in various diseases, including neurodegenerative disorders and certain cancers, making it a significant target for research. Recent studies have shown that RAB9B is essential for the proper maturation of lysosomes and the recycling of growth factor receptors, highlighting its role in maintaining cellular homeostasis. Additionally, RAB9B's interactions with other proteins and its regulatory mechanism have garnered interest in understanding its broader implications in cell signaling and developmental processes. Given the emerging connections between RAB9B dysfunction and disease pathogenesis, researchers are increasingly focused on elucidating the structure-function relationships of this protein, its regulatory pathways, and potential therapeutic targets. This growing interest aims to provide insights into the fundamental mechanisms of cellular transport and to explore the potential of RAB9B as a biomarker or therapeutic target in treating related disorders.
