Cat: PA2000-6112

Recombinant Human C1orf189 Protein,GST

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Analytical Data

  • Gene name

    C1orf189

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    C1orf189; Uncharacterized Protein C1orf189

  • Species

    Human

  • Source

    E. coli

  • Tag

    GST-tag at N-terminal

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q5VU69

  • Expression Region

    1-101aa

  • AA Sequence

    MSVEKMTKVEESFQKAMGLKKTVDRWRNSHTHCLWQMALGQRRNPYATLRMQDTMVQELALAKKQLLMVRQAALHQLFEKEHQQYQQELNQMGKAFYVERF

  • Molecular Weight

    11.2 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

C1orf189, also known as Chromosome 1 open reading frame 189, is a gene located on chromosome 1 that has gained attention in recent years due to its potential role in various biological processes. Initial studies have suggested that C1orf189 may be involved in cellular proliferation and differentiation, positioning it as a candidate gene for investigations in cancer biology and other diseases. The protein encoded by C1orf189 exhibits characteristics indicative of involvement in cellular signaling pathways, though its precise functions remain poorly understood. Additionally, polymorphisms in the C1orf189 gene have been associated with susceptibility to certain autoimmune diseases, further emphasizing the need for comprehensive studies on its role in immune regulation. Researchers aim to develop recombinant C1orf189 protein to elucidate its structural properties and functional mechanisms. By producing this protein in a controlled laboratory environment, scientists can investigate its interactions with other biomolecules and identify potential therapeutic targets. Understanding the role of C1orf189 in disease mechanisms could pave the way for novel diagnostic and therapeutic strategies, making it a significant focus in molecular biology and translational medicine. Through advanced techniques in protein expression and purification, the study of recombinant C1orf189 not only holds promise for illuminating its biological significance but also for contributing to a broader understanding of the molecular basis of diseases linked to this gene.

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