Analytical Data
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Gene name
TPBG
- Application
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Alternative Names
TPBG；5T4；Trophoblast glycoProtein
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q13641
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Expression Region
32-355aa
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AA Sequence
SSPTSSASSFSSSAPFLASAVSAQPPLPDQCPALCECSEAARTVKCVNRNLTEVPTDLPAYVRNLFLTGNQLAVLPAGAFARRPPLAELAALNLSGSRLDEVRAGAFEHLPSLRQLDLSHNPLADLSPFAFSGSNASVSAPSPLVELILNHIVPPEDERQNRSFEGMVVAALLAGRALQGLRRLELASNHFLYLPRDVLAQLPSLRHLDLSNNSLVSLTYVSFRNLTHLESLHLEDNALKVLHNGTLAELQGLPHIRVFLDNNPWVCDCHMADMVTWLKETEVVQGKDRLTCAYPEKMRNRVLLELNSADLDCDPILPPSLQTS
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Molecular Weight
38.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
TPBG (Trophoblast Pregnancy-Specific Glycoprotein) is a glycoprotein that plays a crucial role in pregnancy and embryonic development. Researchers have shown that TPBG is predominantly expressed in human placental trophoblasts, where it is involved in the implantation of the embryo and the modulation of the maternal immune response. Due to its significant role in placental biology, TPBG has garnered attention as a potential biomarker for pregnancy complications such as preeclampsia and fetal growth restrictions. The study of recombinant TPBG proteins is essential for understanding their biological functions and mechanisms of action in the context of pregnancy. By using recombinant DNA technology, scientists can produce large quantities of TPBG, allowing for detailed biochemical and functional analyses. This research aims to elucidate how TPBG interacts with maternal tissues and modulates immune responses, and could lead to the development of diagnostic tools and therapeutic strategies for managing pregnancy-related disorders. Furthermore, investigating the structure-function relationship of TPBG may provide insights into its role in cellular signaling pathways and its potential applications in reproductive medicine. Overall, the exploration of recombinant TPBG not only enhances our understanding of placental biology but also holds promise for advancing prenatal care and improving pregnancy outcomes.
