Analytical Data
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Gene name
RAB20
- Application
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Alternative Names
FLJ20429; RAB20; RAB20 member RAS oncogene family; RAB20_HUMAN; Ras related protein Rab20; Ras-related protein Rab-20
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NX57
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Expression Region
1-234 aa
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AA Sequence
MRKPDSKIVL LGDMNVGKTS LLQRYMERRF PDTVSTVGGA FYLKQWRSYN ISIWDTAGRE QFHGLGSMYC RGAAAIILTY DVNHRQSLVE LEDRFLGLTD TASKDCLFAI VGNKVDLTEE GALAGQEKEE CSPNMDAGDR VSPRAPKQVQ LEDAVALYKK ILKYKMLDEQ DVPAAEQMCF ETSAKTGYNV DLLFETLFDL VVPMILQQRA ERPSHTVDIS SHKPPKRTRS GCCA
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Molecular Weight
26.2 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RAB20 is a member of the RAS oncogene family, recognized for its involvement in intracellular trafficking and membrane fusion processes. Its unique expression patterns and presumed roles in various cellular functions have drawn significant interest within the scientific community. Research has indicated that RAB20 may play a key role in regulating endosomal dynamics, influencing processes such as receptor recycling and degradation. This is particularly relevant in the context of cancer, where disruptions in these trafficking pathways can contribute to tumorigenesis and metastasis. Furthermore, preliminary studies suggest that RAB20 may interact with other proteins involved in autophagy and cell growth, hinting at a multifaceted role in cellular homeostasis. The generation of recombinant RAB20 proteins has enabled researchers to examine its biochemical properties and interactions increasingly closely. By studying these proteins, scientists aim to elucidate the specific mechanisms through which RAB20 exerts its effects and to explore its potential as a therapeutic target. Understanding RAB20's function could pave the way for novel strategies in the treatment of diseases where these cellular processes become dysregulated, highlighting the importance of continued research in this area.
