Analytical Data
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基因名
RAB20
- Application
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别名
FLJ20429; RAB20; RAB20 member RAS oncogene family; RAB20_HUMAN; Ras related protein Rab20; Ras-related protein Rab-20
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NX57
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表达区间
1-234 aa
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氨基酸序列
MRKPDSKIVL LGDMNVGKTS LLQRYMERRF PDTVSTVGGA FYLKQWRSYN ISIWDTAGRE QFHGLGSMYC RGAAAIILTY DVNHRQSLVE LEDRFLGLTD TASKDCLFAI VGNKVDLTEE GALAGQEKEE CSPNMDAGDR VSPRAPKQVQ LEDAVALYKK ILKYKMLDEQ DVPAAEQMCF ETSAKTGYNV DLLFETLFDL VVPMILQQRA ERPSHTVDIS SHKPPKRTRS GCCA
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分子量
26.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RAB20 is a member of the RAS oncogene family, recognized for its involvement in intracellular trafficking and membrane fusion processes. Its unique expression patterns and presumed roles in various cellular functions have drawn significant interest within the scientific community. Research has indicated that RAB20 may play a key role in regulating endosomal dynamics, influencing processes such as receptor recycling and degradation. This is particularly relevant in the context of cancer, where disruptions in these trafficking pathways can contribute to tumorigenesis and metastasis. Furthermore, preliminary studies suggest that RAB20 may interact with other proteins involved in autophagy and cell growth, hinting at a multifaceted role in cellular homeostasis. The generation of recombinant RAB20 proteins has enabled researchers to examine its biochemical properties and interactions increasingly closely. By studying these proteins, scientists aim to elucidate the specific mechanisms through which RAB20 exerts its effects and to explore its potential as a therapeutic target. Understanding RAB20's function could pave the way for novel strategies in the treatment of diseases where these cellular processes become dysregulated, highlighting the importance of continued research in this area.
