Analytical Data
-
基因名
QRSL1
- Application
-
别名
QRSL1; Glutamyl-tRNA(Gln) amidotransferase subunit A; mitochondrial; Glu-AdT subunit A; EC 6.3.5.7; Glutaminyl-tRNA synthase-like protein 1
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9H0R6
-
表达区间
1-528 aa
-
氨基酸序列
MLGRSLREVS AALKQGQITP TELCQKCLSL IKKTKFLNAY ITVSEEVALK QAEESEKRYK NGQSLGDLDG IPIAVKDNFS TSGIETTCAS NMLKGYIPPY NATVVQKLLD QGALLMGKTN LDEFAMGSGS TDGVFGPVKN PWSYSKQYRE KRKQNPHSEN EDSDWLITGG SSGGSAAAVS AFTCYAALGS DTGGSTRNPA AHCGLVGFKP SYGLVSRHGL IPLVNSMDVP GILTRCVDDA AIVLGALAGP DPRDSTTVHE PINKPFMLPS LADVSKLCIG IPKEYLVPEL SSEVQSLWSK AADLFESEGA KVIEVSLPHT SYSIVCYHVL CTSEVASNMA RFDGLQYGHR CDIDVSTEAM YAATRREGFN DVVRGRILSG NFFLLKENYE NYFVKAQKVR RLIANDFVNA FNSGVDVLLT PTTLSEAVPY LEFIKEDNRT RSAQDDIFTQ AVNMAGLPAV SIPVALSNQG LPIGLQFIGR AFCDQQLLTV AKWFEKQVQF PVIQLQELMD DCSAVLENEK LASVSLKQ
-
分子量
57.4 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
QRSL1 (Glutamine-tRNA ligase) is an essential enzyme involved in protein synthesis, specifically in the charging of tRNA with glutamine, which is crucial for accurately translating genetic information into functional proteins. The study of QRSL1 has gained significance due to its pivotal role in cellular processes and its potential implications in various diseases, including cancer and neurodegenerative disorders. Mutations or dysregulation of QRSL1 can lead to impaired protein synthesis and cellular dysfunction, making it a target for therapeutic intervention. Additionally, recent advances in molecular biology techniques have facilitated the detailed characterization of QRSL1, including its structure, function, and interaction with other cellular components. Understanding the molecular mechanisms of QRSL1 not only provides insights into fundamental biological processes but also opens avenues for developing novel strategies to treat diseases associated with its dysfunction. Researchers are now focusing on recombinantly expressing QRSL1 to study its biochemical properties, activity, and potential role as a biomarker, which could lead to innovative approaches in both diagnostics and therapeutics.
