Analytical Data
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基因名
CCL4
- Application
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别名
CCL4；LAG1；MIP1B；SCYA4；C-C motif chemokine 4
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P13236
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表达区间
24-92aa
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氨基酸序列
APMGSDPPTACCFSYTARKLPRNFVVDYYETSSLCSQPAVVFQTKRGKQV CADPSESWVQEYVYDLELN
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分子量
8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCL4, also known as macrophage inflammatory protein-1 beta (MIP-1β), is a chemokine that plays a critical role in immune responses by attracting and activating various immune cells, particularly monocytes and T cells. Its involvement in numerous physiological and pathological processes, such as inflammation, immune regulation, and viral infections, has made CCL4 a significant focus of research in immunology. Understanding the structure and function of CCL4 is essential for elucidating its role in disease mechanisms, including cancer, autoimmune disorders, and HIV pathogenesis. Researchers have utilized recombinant DNA technology to produce CCL4 in significant quantities, allowing for in-depth studies of its biological activities, receptor binding, and interaction with other cytokines. Additionally, recombinant CCL4 has potential therapeutic applications, such as in enhancing immune responses during vaccinations or in developing immune-modulatory therapies. The ongoing study of CCL4 not only deepens our understanding of immune signaling networks but also offers insights into innovative strategies for treating immune-related diseases.
