Analytical Data
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基因名
RS1
- Application
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别名
RS1；XLRS1；Retinoschisin
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O15537
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表达区间
24-224aa
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氨基酸序列
STEDEGEDPWYQKACKCDCQGGPNALWSAGATSLDCIPECPYHKPLGFESGEVTPDQITCSNPEQYVGWYSSWTANKARLNSQGFGCAWLSKFQDSSQWLQIDLKEIKVISGILTQGRCDIDEWMTKYSVQYRTDERLNWIYYKDQTGNNRVFYGNSDRTSTVQNLLRPPIISRFIRLIPLGWHVRIAIRMELLECVSKCA
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分子量
27.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RS1 (retinoschisin 1) is a secreted protein primarily expressed in the retina, playing a crucial role in retinal cell adhesion and communication. Mutations in the RS1 gene are linked to X-linked retinoschisis, a hereditary retinal disorder that leads to vision impairment and often results in retinal detachment. This condition primarily affects males, as it is X-linked, and can manifest early in life. The study of RS1 has garnered attention due to its pivotal role in maintaining the structural integrity of the retina. Researchers have focused on understanding the molecular mechanisms by which RS1 facilitates intercellular interactions among retinal cells, as well as its implications in cellular signaling pathways. Additionally, RS1's potential as a therapeutic target has been explored, with approaches ranging from gene therapy to protein replacement strategies. The pursuit of RS1-related studies aims not only to enhance our comprehension of retinal disorders but also to develop innovative treatment modalities that could restore vision and improve the quality of life for individuals affected by retinoschisis and related diseases.
