Analytical Data
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Gene name
C15orf33
- Application
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Alternative Names
C15orf33; CO033_HUMAN; FAM227B; Uncharacterized Protein C15orf33
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96M60
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Expression Region
1-508aa
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AA Sequence
MAGQRTCQRR SSRAGPGKMQ EPPKSIEEFL KFQNWDYWPR EIHFRDDDKW SCTLKKIKED SSFVSIYTHL WENVPRIFEA LLIMESKLKE YSLILQNHTS EIFKWKSMIS ETSSYRKLER YGEFLKKYHK KKKIMLSDEM ETEKNIEGCS FTGFKANELT QLPRHLDAEQ IYLFILKAHN FDERVFKIWK THFLSEASIA LLHDSFWWWF LHKFRPDREN QDCLFDRISE SYVTLFMSIP LSRKDAFFQI YPDCLAQAIY ATFHEAFPES SYLFNDEFKE DLGNNIFLWC SGLKPQKGFW IHWKLKELST TTIHGSKKAP AKSVKERIAD SQEHISTSID FNIIKILNNP RAYTLPISKE ESRLSRLATK SHYSSTGPEF NRVLFNFGGQ SPLILYYLKM HELAGISKAP KKTKIKLTKI FQEPLPAPTY RDVIKEAKRQ FARNQKDFRI LQAKATKKPH EVKQDFEKFL HKLRSEAEIE RECVASLSSS SSSSPSSTDN YNFEEEEY
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Molecular Weight
59.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
C15orf33, also known as "chromosome 15 open reading frame 33," is a protein-coding gene located on chromosome 15 that has garnered attention in recent years due to its potential roles in various biological processes and diseases. Initially identified through genomic studies, C15orf33 is believed to influence cellular mechanisms such as immune responses and neurodevelopment. Its expression patterns, particularly in the central nervous system and immune tissues, suggest that it may play a role in neuroinflammation and autoimmunity. Researchers have hypothesized that abnormalities in C15orf33 could be linked to neurodegenerative diseases and psychiatric disorders. The generation of recombinant C15orf33 protein has facilitated further studies into its structural properties and functional roles, allowing for the exploration of its interactions with other cellular components. Additionally, studying the effects of mutations or dysregulation of C15orf33 could provide insights into its involvement in disease pathogenesis. Overall, ongoing research into C15orf33 is expected to enhance our understanding of its biological significance and potential therapeutic implications, making it a promising candidate for future investigations in the fields of neurology and immunology.
