Analytical Data
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基因名
PROX1
- Application
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别名
Homeobox prospero like protein; Homeobox prospero like protein PROX1; Homeobox prospero-like protein PROX1; Prospero homeobox 1; Prospero homeobox protein 1; Prospero related homeobox 1; prospero-related homeobox gene 1; PROX 1; PROX-1; PROX1; PROX1_HUMAN; zgc:111888
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q92786
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表达区间
1-737 aa
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氨基酸序列
MPDHDSTALL SRQTKRRRVD IGVKRTVGTA SAFFAKARAT FFSAMNPQGS EQDVEYSVVQ HADGEKSNVL RKLLKRANSY EDAMMPFPGA TIISQLLKNN MNKNGGTEPS FQASGLSSTG SEVHQEDICS NSSRDSPPEC LSPFGRPTMS QFDMDRLCDE HLRAKRARVE NIIRGMSHSP SVALRGNENE REMAPQSVSP RESYRENKRK QKLPQQQQQS FQQLVSARKE QKREERRQLK QQLEDMQKQL RQLQEKFYQI YDSTDSENDE DGNLSEDSMR SEILDARAQD SVGRSDNEMC ELDPGQFIDR ARALIREQEM AENKPKREGN NKERDHGPNS LQPEGKHLAE TLKQELNTAM SQVVDTVVKV FSAKPSRQVP QVFPPLQIPQ ARFAVNGENH NFHTANQRLQ CFGDVIIPNP LDTFGNVQMA SSTDQTEALP LVVRKNSSDQ SASGPAAGGH HQPLHQSPLS ATTGFTTSTF RHPFPLPLMA YPFQSPLGAP SGSFSGKDRA SPESLDLTRD TTSLRTKMSS HHLSHHPCSP AHPPSTAEGL SLSLIKSECG DLQDMSEISP YSGSAMQEGL SPNHLKKAKL MFFYTRYPSS NMLKTYFSDV KFNRCITSQL IKWFSNFREF YYIQMEKYAR QAINDGVTST EELSITRDCE LYRALNMHYN KANDFEVPER FLEVAQITLR EFFNAIIAGK DVDPSWKKAI YKVICKLDSE VPEIFKSPNC LQELLHE
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分子量
83.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PROX1, also known as prospero homeobox 1, is a transcription factor that plays a crucial role in the development and differentiation of various tissues, particularly in the lymphatic system and the central nervous system. Its study has garnered significant attention due to its involvement in key biological processes such as cell proliferation, migration, and fate determination. Aberrant expression of PROX1 has been linked to various diseases, including cancer, where it can influence tumor progression and metastasis. The ability of PROX1 to regulate gene expression makes it a potential target for therapeutic interventions. Research into recombinant PROX1 protein aims to understand its functional mechanisms better, explore its role in cellular signaling pathways, and investigate its potential therapeutic applications. By creating recombinant forms of PROX1, researchers can study its interactions with target genes and proteins, thereby shedding light on its contributions to both physiological and pathological processes. This research landscape not only enhances our understanding of PROX1’s biological significance but also opens avenues for developing novel treatments for diseases associated with its dysregulation.
