Analytical Data
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Gene name
ACOD1
- Application
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Alternative Names
ACOD1；IRG1；Cis-aconitate decarboxylase
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
A6NK06
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Expression Region
1-481aa
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AA Sequence
MMLKSITESFATAIHGLKVGHLTDRVIQRSKRMILDTLGAGFLGTTTEVFHIASQYSKIYSSNISSTVWGQPDIRLPPTYAAFVNGVAIHSMDFDDTWHPATHPSGAVLPVLTALAEALPRSPKFSGLDLLLAFNVGIEVQGRLLHFAKEANDMPKRFHPPSVVGTLGSAAAASKFLGLSSTKCREALAIAVSHAGAPMANAATQTKPLHIGNAAKHGIEAAFLAMLGLQGNKQVLDLEAGFGAFYANYSPKVLPSIASYSWLLDQQDVAFKRFPAHLSTHWVADAAASVRKHLVAERALLPTDYIKRIVLRIPNVQYVNRPFPVSEHEARHSFQYVACAMLLDGGITVPSFHECQINRPQVRELLSKVELEYPPDNLPSFNILYCEISVTLKDGATFTDRSDTFYGHWRKPLSQEDLEEKFRANASKMLSWDTVESLIKIVKNLEDLEDCSVLTTLLKGPSPPEVASNSPACNNSITNLS
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Molecular Weight
58.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ACOD1 (Amino Acid Cysteine-type Decarboxylase 1) is an enzyme that plays a pivotal role in the catabolism of amino acids, particularly in the context of immune response regulation and metabolic pathways. Research has illuminated its significance in modulating inflammatory responses, particularly through the production of metabolites that can affect cellular signaling pathways. The interest in ACOD1 has surged due to its potential implications in various diseases, such as autoimmune disorders, obesity, and cancer, where metabolic dysregulation and inflammation are key factors. Recombination techniques for producing ACOD1 allow for the examination of its structure-function relationships, interaction with other biomolecules, and the impact of specific mutations on its enzymatic activity. Additionally, the recombinant protein serves as a valuable tool for drug development and therapeutic interventions aimed at modulating its activity to restore balance in immune functions. Understanding ACOD1's biochemical properties and its role in physiological and pathological contexts continues to be of paramount importance, paving the way for innovative approaches in treating related diseases.
