Analytical Data
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Gene name
IP6K1
- Application
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Alternative Names
IP6K1;IHPK1;KIAA0263;Inositol hexakisphosphate kinase 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q92551
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Expression Region
1-441aa
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AA Sequence
MCVCQTMEVGQYGKNASRAGDRGVLLEPFIHQVGGHSSMMRYDDHTVCKP LISREQRFYESLPPEMKEFTPEYKGVVSVCFEGDSDGYINLVAYPYVESE TVEQDDTTEREQPRRKHSRRSLHRSGSGSDHKEEKASLSLETSESSQEAK SPKVELHSHSEVPFQMLDGNSGLSSEKISHNPWSLRCHKQQLSRMRSESK DRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEKAARQMRKCEQ STSATLGVRVCGMQVYQLDTGHYLCRNKYYGRGLSIEGFRNALYQYLHNG LDLRRDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECRAESCL DRRSEMRLKHLDMVLPEVASSCGPSTSPSNTSPEAGPSSQPKVDVRMIDF AHSTFKGFRDDPTVHDGPDRGYVFGLENLISIMEQMRDENQ
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Molecular Weight
66 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of IP6K1 (inositol hexakisphosphate kinases 1) has gained considerable attention due to its critical role in cellular processes and signaling pathways. IP6K1 is an enzyme that phosphorylates inositol hexakisphosphate (IP6) to generate inositol pyrophosphates, which are involved in regulating various biological functions, including cell proliferation, apoptosis, and energy metabolism. Dysregulation of IP6K1 has been implicated in several pathological conditions, including cancer and metabolic disorders, making it a potential target for therapeutic interventions. Research has shown that IP6K1 can influence insulin signaling, suggesting its involvement in glucose homeostasis and insulin resistance. Moreover, IP6K1's interaction with other molecules in cellular signaling cascades highlights its multifaceted role in modulating cellular responses to external stimuli. As scientists continue to explore the complex biochemical pathways associated with IP6K1, this research not only enhances our understanding of cellular physiology but also paves the way for new strategies to manage diseases associated with IP6K1 dysregulation.











