Analytical Data
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Gene name
CTRC
- Application
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Alternative Names
CTRC；CLCR；Chymotrypsin-C
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q99895
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Expression Region
30-268aa
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AA Sequence
VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLLRNDIALIKLAEHVELSDTIQVACLPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQL
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Molecular Weight
28.1 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CTRC (Cationic Trypsinogen-Related Protein) is a serine protease that has garnered significant attention in biomedical research due to its role in various physiological and pathological processes. Originally identified as a pancreatic enzyme, CTRC is implicated in the regulation of digestive processes and has been linked to diseases such as pancreatitis and pancreatic cancer. Studies have shown that mutations in the CTRC gene can lead to an increased risk of chronic pancreatitis, highlighting its importance in pancreatic health. The protein’s functionality extends beyond digestion; it has also been associated with immune responses and inflammation. Given its critical roles, the recombinant expression of CTRC has become a focal point for investigating its enzymatic characteristics, structure-function relationships, and potential therapeutic applications. The recombinant protein can facilitate high-throughput studies and drug discovery efforts aimed at targeting CTRC-related pathways in human diseases. Furthermore, understanding CTRC's molecular mechanisms may pave the way for novel approaches in treating pancreatic disorders, making it a valuable target in both basic and translational research. As a result, ongoing studies aim to elucidate the precise role of CTRC in normal physiology and disease, thereby contributing to the broader understanding of pancreatic biology and potential therapeutic interventions.
