Cat: PA1000-4370

Recombinant Human Alpl Protein,His

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Analytical Data

  • 基因名

    Alpl

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    Alpl;Alkaline phosphatase. tissue-nonspecific isozyme

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P05186

  • 表达区间

    29-138aa

  • 氨基酸序列

    WRDQAQETLKYALELQKLNTNVAKNVIMFLGDGMGVSTVTAARILKGQLH HNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCGVKANEGTV GVSAATERSR

  • 分子量

    38 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

Alpl, also known as alkaline phosphatase, is an essential enzyme in various biological processes, particularly in mineralization, which is crucial for bone formation and maintenance. The study of Alpl recombinant proteins has gained significant attention due to their potential applications in both basic research and clinical settings. Understanding the structure-function relationship of Alpl can unveil insights into metabolic bone disorders, such as osteomalacia, rickets, and other diseases resulting from dysfunctional mineralization. The recombinant expression of Alpl allows for the production of large quantities of this enzyme, enabling detailed studies on its enzymatic activity, regulation, and interaction with substrates. Furthermore, recombinant Alpl is increasingly being explored for therapeutic applications, particularly in the treatment of skeletal diseases and age-related bone loss, where enhancing bone resorption and mineralization may be beneficial. Advances in recombinant DNA technology and protein engineering have facilitated the design of modified versions of Alpl, improving stability, activity, and specificity for therapeutic purposes. Overall, the exploration of Alpl recombinant proteins is a promising area of research that bridges fundamental biology and potential clinical therapies, paving the way for innovative strategies in treating bone-related disorders.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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