Recombinant Human ANAPC15 Protein，His

ANAPC15, also known as APC15 or Cdc20, is an essential component of the Anaphase Promoting Complex/Cyclosome (APC/C), a crucial E3 ubiquitin ligase in the cell cycle regulation. The primary function of APCC is to target specific proteins for destruction via ubiquitination, thereby facilitating the transition from metaphase to anaphase during cell division. Understanding the structure and function of ANAPC15 is vital, as its dysfunction is often linked to various cancers and other diseases characterized by abnormal cell proliferation. Studies have indicated that ANAPC15 interacts with multiple co-factors, including Cdc20 and other regulatory proteins, to ensure precise timing of substrate recognition and ubiquitination. Research into the molecular structure of ANAPC15 has unveiled insights into its role in controlling protein degradation pathways, maintaining genomic stability, and preventing tumorigenesis. Moreover, the investigation of ANAPC15 in different cellular contexts has led to a better understanding of its regulation under stress conditions and its contributions to various signaling pathways. The development of recombinant ANAPC15 proteins for experimental use has become crucial for elucidating its biochemical properties and interactions within the APC/C complex, contributing significantly to cell cycle research and therapeutic developments targeting aberrant cell division in cancer. Overall, ANAPC15 represents a pivotal area of study in molecular and cellular biology, with implications for both fundamental science and clinical applications.