Analytical Data
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Gene name
C11orf84
- Application
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Alternative Names
SPINDOC; C11orf84; Spindlin interactor and repressor of chromatin-binding Protein
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9BUA3
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Expression Region
1-381aa
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AA Sequence
MALKAEGAAL DCFEVTLKCE EGEDEEEAMV VAVIPRPEPM LRVTQQEKTP PPRPSPLEAG SDGCEEPKQQ VSWEQEFLVG SSPGGSGRAL CMVCGAEIRA PSADTARSHI LEQHPHTLDL SPSEKSNILE AWSEGVALLQ DVRAEQPSPP NSDSGQDAHP DPDANPDAAR MPAEIVVLLD SEDNPSLPKR SRPRGLRPLE LPAVPATEPG NKKPRGQRWK EPPGEEPVRK KRGRPMTKNL DPDPEPPSPD SPTETFAAPA EVRHFTDGSF PAGFVLQLFS HTQLRGPDSK DSPKDREVAE GGLPRAESPS PAPPPGLRGT LDLQVIRVRM EEPPAVSLLQ DWSRHPQGTK RVGAGDTSDW PTVLSESSTT VAGKPEKGNG V
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Molecular Weight
67.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
C11orf84 is a gene located on chromosome 11 that has garnered attention due to its potential role in various cellular processes and associated diseases. Recent studies have suggested that C11orf84 may be involved in neurodevelopmental disorders and cancer, making it an important target for biomedical research. The gene's protein product is thought to participate in intracellular signaling pathways and regulation of gene expression, but its exact biological function remains largely unknown. The recombinant C11orf84 protein is generated to facilitate the study of its molecular characteristics and interactions. By producing this protein in a laboratory setting, researchers aim to elucidate its structure, function, and potential roles in disease mechanisms. Understanding the properties of C11orf84 could pave the way for innovative therapeutic strategies, particularly in conditions where dysregulation of this protein might contribute to pathology. The exploration of recombinant C11orf84 also allows for the investigation of its potential as a biomarker for diagnosis or prognosis in relevant diseases. Thus, ongoing research into C11orf84 and its recombinant form stands to provide significant insights into its biological significance and therapeutic potential.
