Analytical Data
-
基因名
PPP1R21
- Application
-
别名
PPP1R21; CCDC128; KLRAQ1; Protein phosphatase 1 regulatory subunit 21; Coiled-coil domain-containing protein 128; KLRAQ motif-containing protein 1
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q6ZMI0
-
表达区间
1-780 aa
-
氨基酸序列
MASAELQGKY QKLAQEYSKL RAQNQVLKKG VVDEQANSAA LKEQLKMKDQ SLRKLQQEMD SLTFRNLQLA KRVELLQDEL ALSEPRGKKN KKSGESSSQL SQEQKSVFDE DLQKKIEENE RLHIQFFEAD EQHKHVEAEL RSRLATLETE AAQHQAVVDG LTRKYMETIE KLQNDKAKLE VKSQTLEKEA KECRLRTEEC QLQLKTLHED LSGRLEESLS IINEKVPFND TKYSQYNALN VPLHNRRHQL KMRDIAGQAL AFVQDLVTAL LNFHTYTEQR IQIFPVDSAI DTISPLNQKF SQYLHENASY VRPLEEGMLH LFESITEDTV TVLETTVKLK TFSEHLTSYI CFLRKILPYQ LKSLEEECES SLCTSALRAR NLELSQDMKK MTAVFEKLQT YIALLALPST EPDGLLRTNY SSVLTNVGAA LHGFHDVMKD ISKHYSQKAA IEHELPTATQ KLITTNDCIL SSVVALTNGA GKIASFFSNN LDYFIASLSY GPKAASGFIS PLSAECMLQY KKKAAAYMKS LRKPLLESVP YEEALANRRI LLSSTESREG LAQQVQQSLE KISKLEQEKE HWMLEAQLAK IKLEKENQRI ADKLKNTGSA QLVGLAQENA AVSNTAGQDE ATAKAVLEPI QSTSLIGTLT RTSDSEVPDV ESREDLIKNH YMARIVELTS QLQLADSKSV HFYAECRALS KRLALAEKSK EALTEEMKLA SQNISRLQDE LTTTKRSYED QLSMMSDHLC SMNETLSKQR EEIDTLKMSS KGNSKKNKSR
-
分子量
88.3 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PPP1R21, also known as Protein Phosphatase 1 Regulatory Subunit 21, is a member of the protein phosphatase 1 (PP1) regulatory subunit family, which plays a critical role in regulating various cellular processes, including cell division, metabolism, and signal transduction. The research on PPP1R21 has gained attention due to its potential implications in cancer biology and other diseases. Studies have shown that PPP1R21 may influence the activity of PP1, a serine/threonine phosphatase that is key in numerous signaling pathways. By modulating PP1 activity, PPP1R21 could affect cellular responses to growth factors, stress, and apoptosis. Recent investigations have focused on elucidating the structural characteristics of PPP1R21, as well as its interaction with PP1 and other cellular partners. Understanding the functional dynamics of PPP1R21 is essential for delineating its role in normal physiology and disease pathology. This protein is also being explored as a potential therapeutic target, making the development of recombinant PPP1R21 crucial for further studies. Efforts to produce and characterize this protein recombinantly are aimed at providing insights into its regulatory mechanisms, offering a better understanding of its influence in various diseases, including cancer and neurodegenerative disorders. Ultimately, the ongoing research on PPP1R21 could contribute to the development of new therapeutic strategies that target its regulatory pathways.
