Analytical Data
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Gene name
C11orf20
- Application
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Alternative Names
CATSPERZ; C11orf20; TEX40Cation channel sperm-associated Protein subunit zeta; CatSper-zeta; CatSperzeta; Testis-expressed Protein 40
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NTU4
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Expression Region
1-200aa
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AA Sequence
MEEKPSKVSL KSSDRQGSDE ESVHSDTRDL WTTTTLSQAQ LNMPLSEVCE GFDEEGRNIS KTRGWHSPGR GSLDEGYKAS HKPEELDEHA LVELELHRGS SMEINLGEKD TASQIEAEKS SSMSSLNIAK HMPHRAYWAE QQSRLPLPLM ELMENEALEI LTKALRSYQL GIGRDHFLTK ELQRYIEGLK KRRSKRLYVN
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Molecular Weight
200 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
C11orf20, also known as "Chromosome 11 Open Reading Frame 20", has garnered significant interest in biomedical research due to its association with various neurological disorders. Initially identified through genomic studies, C11orf20 is located on chromosome 11 and is thought to play a crucial role in neuronal function and development. Recent advancements in mass spectrometry and proteomics have enabled the recombinant production of C11orf20 protein, facilitating in-depth studies of its biological functions and mechanisms. Research has indicated that C11orf20 may be implicated in the regulation of gene expression and cellular signaling pathways, which are vital for maintaining neuronal health. Additionally, mutations in the C11orf20 gene have been linked to conditions such as neurodevelopmental disorders and epilepsy, highlighting its potential as a therapeutic target. As scientists continue to explore the properties and interactions of the C11orf20 protein, these investigations aim to uncover its role in disease mechanisms, paving the way for novel diagnostic and therapeutic approaches in neurology. Understanding the structure and function of recombinant C11orf20 is essential for elucidating its potential contributions to both normal brain function and pathological conditions.
