Analytical Data
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基因名
POU3F1
- Application
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别名
POU domain. class 3. transcription factor 1. Octamer-binding protein 6. Oct-6. Octamer-binding transcription factor 6. OTF-6. POU domain transcription factor SCIP
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q03052
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表达区间
1-451 aa
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氨基酸序列
MATTAQYLPRGPGGGAGGTGPLMHPDAAAAAAAAAAAERLHAGAAYREVQKLMHHEWLGAGAGHPVGLAHPQWLPTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQGAAHAGAAWAQGSTAHHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLAGMLAAGGGGAGPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSSVGEHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADVGLALGTLYGNVFSQTTICRFEALQLSFKNMCKLKPLLNKWLEETDSSSGSPTNLDKIAAQGRKRKKRTSIEVGVKGALESHFLKCPKPSAHEITGLADSLQLEKEVVRVWFCNRRQKEKRMTPAAGAGHPPMDDVYAPGELGPGGGGASPPSAPPPPPPAALHHHHHHTLPGSVQ
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分子量
76.01 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
POU3F1, also known as Oct-6 or OTF-1, is a member of the POU family of transcription factors that plays crucial roles in various biological processes, including brain development, cellular differentiation, and the maintenance of stem cell characteristics. Its expression is predominantly localized in the central nervous system, where it is essential for neuronal lineage specification and maturation. Recent studies have highlighted POU3F1's involvement in various neural-related diseases, including certain cancers and neurodegenerative disorders, suggesting its potential as a therapeutic target. The recombinant protein of POU3F1 has gained attention in research due to its ability to interact with specific DNA sequences, thereby influencing gene expression patterns. Investigating the functional dynamics of POU3F1 through recombinant technology enables researchers to dissect its mechanistic roles in gene regulation and cellular processes, illuminating its contribution to both normal physiology and pathological conditions. Furthermore, understanding POU3F1’s structure-function relationship could pave the way for novel interventions in diseases linked to neuronal dysfunction. As the field progresses, the exploration of POU3F1 recombinant protein not only advances our knowledge of transcriptional regulation in neuronal biology but also opens avenues for innovative therapeutic approaches in neurobiology and regenerative medicine.
