Analytical Data
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基因名
C10orf46
- Application
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别名
CACUL1; C10orf46; CAC1CDK2-associated and cullin domain-containing Protein 1; Cdk-associated cullin1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q86Y37
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表达区间
1-369aa
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氨基酸序列
MEESMEEEEG GSYEAMMDDQ NHNNWEAAVD GFRQPLPPPP PPSSIPAPAR EPPGGQLLAV PAVSVDRKGP KEGLPMGPQP PPEANGVIMM LKSCDAAAAV AKAAPAPTAS STININTSTS KFLMNVITIE DYKSTYWPKL DGAIDQLLTQ SPGDYIPISY EQIYSCVYKC VCQQHSEQMY SDLIKKITNH LERVSKELQA SPPDLYIERF NIALGQYMGA LQSIVPLFIY MNKFYIETKL NRDLKDDLIK LFTEHVAEKH IYSLMPLLLE AQSTPFQVTP STMANIVKGL YTLRPEWVQM APTLFSKFIP NILPPAVESE LSEYAAQDQK FQRELIQNGF TRGDQSRKRA GDELAYNSSS ACASSRGYR
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分子量
41 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
C10orf46, also known as SLC39A10, is a gene located on chromosome 10 that has garnered attention due to its potential roles in human biology and disease. Recent studies have identified C10orf46 as being involved in several cellular processes, including zinc homeostasis and cellular signaling. Aberrant expression of C10orf46 has been implicated in various pathologies, particularly in cancer, where its dysregulation may influence tumor growth and metastasis. Additionally, the protein's involvement in immune responses highlights its relevance in understanding autoimmune diseases. Researchers are increasingly focused on characterizing the recombinant protein of C10orf46 to elucidate its structure-function relationships and explore potential therapeutic applications. The recombinant protein can serve as a valuable tool for studying the protein's interactions with other cellular components and its regulatory pathways. Moreover, understanding the biochemical properties of C10orf46 may lead to the identification of novel biomarkers or targets for therapeutic intervention. As research progresses, insights gained from C10orf46 could inform strategies for diagnostics and treatment, particularly in contexts where its function is disrupted. The continuous exploration of C10orf46 not only enhances our understanding of its biological roles but also opens avenues for innovative research that could significantly impact medical science.
