Analytical Data
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Gene name
BTN2A3P
- Application
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Alternative Names
BTN2A3P; BTN2A3Putative butyrophilin subfamily 2 member A3
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96KV6
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Expression Region
1-586aa
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AA Sequence
MEPAAALHFSRPASLLLLLSLCALVSAQVTVVGPTDPILAMVGENTTLRCCLSPEENAEDMEVRWFQSQFSPAVFVYKGGRERTEEQKEEYRGRTTFVSKDSRGSVALIIHNVTAEDNGIYQCYFQEGRSCNEAILHLVVAGLDSEPVIEMRDHEDGGIQLECISGGWYPKPLTVWRDPYGEVVPALKEVSTPDADSLFMVTTAVIIRDKSVRNVSCSINDTLLGQKKESVIFIPESFMPSRSPCVVILPVIMIILMIPIAICIYWINNLQKEKKDSHLMTFNLCLSLAGWRRTFLHAANVVLDQDTGHPYLFVSEDKRSVTLDPSRESIPGNPERFDSQLCVLGQESFASGKHYLEVDVENVIEWTVGICRDNVERKWEVPLLPQNGFWTLEMHKRKYWALTSLKWILSLEEPLCQVGIFLDYEAGDVSFYNMRDRSHIYTFPHSAFSVPVRPFFSLGSYDSQILICSAFTGASGVTVPEEGWTLHRAGTHHSPQNQFPSLTAMETSPGHLSSHCTMPLVEDTPSSPLVTQENIFQLPLSHPLQTSAPVHLLIRCGFSSSFGCNYGMESRHRELVVPQLPARKKV
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Molecular Weight
65.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
BTN2A3P, a member of the BTN (B7-like) family of proteins, has garnered interest in recent years due to its potential implications in immune regulation and cancer biology. The BTN family is known for its role in modulating immune responses, particularly as ligands for immune checkpoints. BTN2A3P, specifically, is a pseudogene with a complex evolutionary history, and while it shares homology with other BTN family members, its functional role has not been thoroughly characterized. Recent studies have suggested that BTN2A3P may be involved in tumor immune evasion mechanisms, potentially influencing T cell activation and polarization. Investigating the recombinant protein of BTN2A3P can provide critical insights into its structure, function, and interactions within the immune system. Understanding how BTN2A3P modulates immune responses could unveil new therapeutic targets for cancer treatment and enhance the efficacy of immunotherapies. The development of recombinant BTN2A3P protein could also facilitate the exploration of its binding partners, signaling pathways, and biological activity, paving the way for innovative strategies to manipulate immune responses in various diseases. This research emphasizes the need to delve deeper into the underexplored realm of pseudogenes, expanding our knowledge of their contributions to health and disease.
