Analytical Data
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Gene name
BTG4
- Application
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Alternative Names
B cell translocation gene 4; BTG family member 4; Btg4; BTG4_HUMAN; MGC33003; PC3B ; Protein BTG4; Protein PC3b
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NY30
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Expression Region
1-223aa
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AA Sequence
MRDEIATTVF FVTRLVKKHD KLSKQQIEDF AEKLMTILFE TYRSHWHSDC PSKGQAFRCI RINNNQNKDP ILERACVESN VDFSHLGLPK EMTIWVDPFE VCCRYGEKNH PFTVASFKGR WEEWELYQQI SYAVSRASSD VSSGTSCDEE SCSKEPRVIP KVSNPKSIYQ VENLKQPFQS WLQIPRKKNV VDGRVGLLGN TYHGSQKHPK CYRPAMHRLD RIL
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Molecular Weight
25.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
BTG4 (B-cell translocation gene 4) is a member of the BTG/Tob family of proteins, which are implicated in various cellular processes, including cell proliferation, differentiation, and apoptosis. Research into BTG4 has gained momentum due to its potential role in regulating tumorigenesis and its association with various cancers, particularly in hematopoietic malignancies. This protein functions as a transcriptional co-repressor and is believed to modulate the activity of several key signaling pathways, including those related to cell cycle regulation. Recent studies have focused on the recombinant expression of BTG4 to elucidate its functional mechanisms, allowing for investigations into its interactions with other proteins and molecular partners within the cell. By generating recombinant BTG4 in suitable expression systems, researchers aim to produce sufficient quantities of the protein for detailed structural and functional analyses. This research is critical not only for understanding the biological pathways involving BTG4 but also for exploring its therapeutic potential in cancer treatment strategies. Given the ongoing discoveries regarding its involvement in cellular signaling and cancer progression, BTG4 holds promise as a biomarker or target for intervention, highlighting the importance of further studies on its recombinant protein.
