Analytical Data
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基因名
BTG2
- Application
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别名
B cell translocation gene 2; BTG family member 2; Btg2; BTG2_HUMAN
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P78543
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表达区间
1-158aa
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氨基酸序列
MSHGKGTDML PEIAAAVGFL SSLLRTRGCV SEQRLKVFSG ALQEALTEHY KHHWFPEKPS KGSGYRCIRI NHKMDPIISR VASQIGLSQP QLHQLLPSEL TLWVDPYEVS YRIGEDGSIC VLYEEAPLAA SCGLLTCKNQ VLLGRSSPSK NYVMAVSS
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分子量
17.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
BTG2 (B-cell translocation gene 2) is a member of the BTG family of proteins, which are known for their roles in regulating cell cycle progression, differentiation, and apoptosis. Research on BTG2 has gained momentum due to its potential implications in cancer biology and other diseases. Specifically, BTG2 functions as a tumor suppressor, inhibiting cell proliferation and promoting apoptosis in various cancer types, including breast and colorectal cancers. Its expression is often downregulated in cancerous tissues, which correlates with poor prognosis and aggressive tumor behavior. Recombination and expression studies of BTG2 have been pivotal in elucidating its molecular mechanisms, involving the regulation of genes associated with cell growth and survival. Moreover, BTG2's interactions with other signaling pathways, such as the p53 tumor suppressor pathway, underscore its importance in maintaining cellular homeostasis. Understanding the structure and function of recombinantly expressed BTG2 can provide insights into its role in tumorigenesis and may reveal potential therapeutic targets for cancer treatment. Additionally, the study of BTG2’s role in cellular response to stress and differentiation emphasizes its relevance beyond cancer, potentially contributing to the understanding of neurodegenerative diseases and developmental processes. Overall, the investigation of BTG2 recombinant proteins offers a promising avenue for advancing our knowledge of its biological functions and therapeutic applications.












