Cat: PA2000-5853

Recombinant Human BTBD9 Protein,His

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Analytical Data

  • Gene name

    BTBD9

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    BTB/POZ domain-containing Protein 9; Btbd9; BTBD9_HUMAN

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q96Q07

  • Expression Region

    1-612aa

  • AA Sequence

    MSNSHPLRPF TAVGEIDHVH ILSEHIGALL IGEEYGDVTF VVEKKRFPAH RVILAARCQY FRALLYGGMR ESQPEAEIPL QDTTAEAFTM LLKYIYTGRA TLTDEKEEVL LDFLSLAHKY GFPELEDSTS EYLCTILNIQ NVCMTFDVAS LYSLPKLTCM CCMFMDRNAQ EVLSSEGFLS LSKTALLNIV LRDSFAAPEK DIFLALLNWC KHNSKENHAE IMQAVRLPLM SLTELLNVVR PSGLLSPDAI LDAIKVRSES RDMDLNYRGM LIPEENIATM KYGAQVVKGE LKSALLDGDT QNYDLDHGFS RHPIDDDCRS GIEIKLGQPS IINHIRILLW DRDSRSYSYF IEVSMDELDW VRVIDHSQYL CRSWQKLYFP ARVCRYIRIV GTHNTVNKIF HIVAFECMFT NKTFTLEKGL IVPMENVATI ADCASVIEGV SRSRNALLNG DTKNYDWDSG YTCHQLGSGA IVVQLAQPYM IGSIRLLLWD CDDRSYSYYV EVSTNQQQWT MVADRTKVSC KSWQSVTFER QPASFIRIVG THNTANEVFH CVHFECPEQQ SSQKEENSEE SGTGDTSLAG QQLDSHALRA PSGSSLPSSP GSNSRSPNRQ HQ

  • Molecular Weight

    69.1 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

BTBD9 is a member of the BTB (Broad-Complex, Tramtrack, and Bric-a-brac) domain-containing protein family, which plays a critical role in various biological processes, including transcriptional regulation and cellular signaling. Emerging evidence suggests that BTBD9 is implicated in several physiological functions and has been associated with various diseases, particularly in the context of neurodegenerative disorders and sleep regulation. For instance, studies have shown that variants in the BTBD9 gene are linked to increased risk of developing Parkinson's disease and other movement disorders, highlighting its significance in neurological health. Additionally, BTBD9 has been identified as a player in the regulation of iron homeostasis, thereby influencing metabolic pathways. The reconstitution and functional analysis of BTBD9 in experimental settings allow researchers to delve deeper into its molecular mechanisms and interactions, paving the way for potential therapeutic strategies. Understanding the structural and functional properties of BTBD9 through the study of recombinant proteins may provide valuable insights into its role in disease and cellular function, ultimately contributing to the development of targeted interventions in related health issues. As such, BTBD9 represents a vital area for ongoing research, aiming to elucidate its contributions to human health and disease.

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