Analytical Data
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Gene name
BRUNOL6
- Application
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Alternative Names
6330569O16Rik; Bruno like 6; RNA binding Protein (Drosophila); bruno like 6; RNA binding Protein; Bruno like Protein 6; Bruno-like Protein 6; BRUNOL6
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96J87
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Expression Region
1-481aa
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AA Sequence
MTAAPGGSAQPAGPGPRLGFSTADSGVGMSGLNPGPAVPMKDHDAIKLFVGQIPRGLDEQDLKPLFEEFGRIYELTVLKDRLTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPAASEGRGEDRKLFVGMLGKQQGEEDVRRLFQPFGHIEECTVLRSPDGTSKGCAFVKFGSQGEAQAAIRGLHGSRTMAGASSSLVVKLADTDRERALRRMQQMAGHLGAFHPAPLPLGACGAYTTAILQHQAALLAAAQGPGLGPVAAVAAQMQHVAAFSLVAAPLLPAAAANSPPGSGPGTLPGLPAPIGVNGFGPLTPQTNGQPGSDTLYNNGLSPYPAQSPGVADPLQQAYAGMHHYAAAYPSAYAPVSTAFPQQPSALPQQQREGPEGCNLFIYHLPQEFGDAELIQTFLPFGAVVSAKVFVDRATNQSKCFGFVSFDNPTSAQTAIQAMNGFQIGMKRLKAQLKRPKDANRPY
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Molecular Weight
76.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
BRUNOL6, a member of the BRUNO-like protein family, plays a crucial role in post-transcriptional regulation and RNA metabolism. Emerging evidence suggests that BRUNOL6 is involved in various cellular processes, including RNA splicing, stability, localization, and translation. Its expression has been linked to several key developmental stages, particularly in the neural and reproductive systems, indicating its potential role in early embryogenesis and stem cell maintenance. Furthermore, dysregulation of BRUNOL6 has been implicated in various diseases, including cancer, highlighting its significance in understanding pathogenic mechanisms. Research into BRUNOL6 utilizes advanced techniques such as RNA sequencing and CRISPR-Cas9 gene editing to elucidate its functional properties and interactions with other RNA-binding proteins. This growing body of work aims to clarify BRUNOL6's specific roles in cellular events and its potential as a therapeutic target, particularly in oncological contexts. As such, BRUNOL6 represents a promising avenue of investigation in the field of molecular biology, with implications for both basic research and clinical applications.
