Analytical Data
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Gene name
CELA2B
- Application
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Alternative Names
CELA2B;ELA2B;Chymotrypsin-like elastase family member 2B
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P08218
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Expression Region
29-269aa
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AA Sequence
MLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHCISSSGIYRVMLGQHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGNDIALLKLANPVSLTDKIQLACLPPAGTILPNNYPCYVTGWGRLQTNGALPDDLKQGQLLVVDYATCSSSGWWGSTVKTNMICAGGDGVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSVLGCNYYYKPSIFTRVSNYNDWINSVIANN
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Molecular Weight
38.8 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CELA2B is a novel recombinant protein that stems from research focused on the characterization of the serine protease family, particularly those implicated in various biological processes, including inflammation, immunity, and blood coagulation. Initial studies revealed that CELA2B exhibits distinct enzymatic properties that differentiate it from closely related proteases, prompting investigations into its structure-function relationships and potential applications in biotechnology and medicine. Researchers have identified CELA2B's unique substrate specificity and activity profile, suggesting its possible role in pathological conditions such as cancer and autoimmune diseases. The development of recombinant CELA2B allows for the production of this protein in a controlled environment, facilitating detailed study of its functional mechanisms and interactions with other biomolecules. Advancements in techniques like CRISPR/Cas9 genome editing and synthetic biology have further enhanced the ability to manipulate CELA2B, offering insights into its therapeutic potentials. Moreover, understanding how CELA2B regulates cellular processes at a molecular level may contribute to the development of novel therapeutic strategies, highlighting the importance of this protein in both basic research and clinical applications. As such, the exploration of CELA2B underscores the ongoing need for comprehensive studies in the field of proteomics and enzyme research, with implications for developing targeted therapies and diagnostics.











