Analytical Data
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Gene name
PLEK2
- Application
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Alternative Names
Pleckstrin 2 (mouse) homolog; Pleckstrin 2; Pleckstrin-2; PLEK 2; PLEK2; PLEK2_HUMAN
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9NYT0
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Expression Region
1-353 aa
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AA Sequence
MEDGVLKEGF LVKRGHIVHN WKARWFILRQ NTLVYYKLEG GRRVTPPKGR ILLDGCTITC PCLEYENRPL LIKLKTQTST EYFLEACSRE ERDAWAFEIT GAIHAGQPGK VQQLHSLRNS FKLPPHISLH RIVDKMHDSN TGIRSSPNME QGSTYKKTFL GSSLVDWLIS NSFTASRLEA VTLASMLMEE NFLRPVGVRS MGAIRSGDLA EQFLDDSTAL YTFAESYKKK ISPKEEISLS TVELSGTVVK QGYLAKQGHK RKNWKVRRFV LRKDPAFLHY YDPSKEENRP VGGFSLRGSL VSALEDNGVP TGVKGNVQGN LFKVITKDDT HYYIQASSKA ERAEWIEAIK KLT
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Molecular Weight
39.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PLEK2 is a pivotal protein that plays a significant role in various cellular processes, including cytoskeletal dynamics and cell signaling. As a member of the PLEK family, PLEK2 has been implicated in regulating cellular responses to environmental stimuli, influencing cellular morphology, migration, and adhesion. Recent studies have highlighted its involvement in critical pathways related to cancer progression, immune response, and neurological functions. Due to its multifaceted roles, researchers have increasingly focused on recombinant PLEK2 proteins to unravel their specific functions and mechanisms. The generation of PLEK2 recombinant proteins allows for detailed structural and functional analyses, facilitating the understanding of its interactions with other proteins and cellular components. Additionally, elucidating the role of PLEK2 in pathophysiological conditions may pave the way for novel therapeutic strategies, particularly in targeting diseases where PLEK2 dysregulation is observed. Thus, the development and characterization of PLEK2 recombinant proteins are essential for advancing our understanding of this crucial protein in health and disease contexts.
