Analytical Data
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Gene name
ZFAND1
- Application
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Alternative Names
ZFAND1；AN1-type zinc finger Protein 1
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8TCF1
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Expression Region
1-268aa
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AA Sequence
MAELDIGQHC QVEHCRQRDF LPFVCDDCSG IFCLEHRSRE SHGCPEVTVI NERLKTDQHT SYPCSFKDCA ERELVAVICP YCEKNFCLRH RHQSDHECEK LEIPKPRMAA TQKLVKDIID SKTGETASKR WKGAKNSETA AKVALMKLKM HADGDKSLPQ TERIYFQVFL PKGSKEKSKP MFFCHRWSIG KAIDFAASLA RLKNDNNKFT AKKLRLCHIT SGEALPLDHT LETWIAKEDC PLYNGGNIIL EYLNDEEQFC KNVESYLE
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ZFAND1, a member of the ZFAND family of proteins, plays a crucial role in various cellular processes, including protein degradation, apoptosis, and cellular stress responses. It is characterized by the presence of zinc finger motifs, which are fundamental for its interaction with other proteins and regulatory elements. Research has shown that ZFAND1 is implicated in the modulation of the ubiquitin-proteasome system, influencing protein turnover and maintaining cellular homeostasis. Abnormal expression or mutations in ZFAND1 have been associated with multiple diseases, including cancer and neurodegenerative disorders, highlighting its potential as a therapeutic target. Moreover, studies suggest that ZFAND1 may also be involved in immune responses, acting as a regulator of inflammatory pathways. Recent advancements in structural biology have enabled the detailed characterization of ZFAND1, providing insight into its functional mechanisms and interactions within the cell. As researchers continue to unravel the complexities of ZFAND1, it is becoming increasingly evident that understanding its role in cellular dynamics could lead to novel strategies for disease intervention and treatment.
