Analytical Data
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基因名
ZFAND1
- Application
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别名
ZFAND1；AN1-type zinc finger Protein 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8TCF1
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表达区间
1-268aa
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氨基酸序列
MAELDIGQHC QVEHCRQRDF LPFVCDDCSG IFCLEHRSRE SHGCPEVTVI NERLKTDQHT SYPCSFKDCA ERELVAVICP YCEKNFCLRH RHQSDHECEK LEIPKPRMAA TQKLVKDIID SKTGETASKR WKGAKNSETA AKVALMKLKM HADGDKSLPQ TERIYFQVFL PKGSKEKSKP MFFCHRWSIG KAIDFAASLA RLKNDNNKFT AKKLRLCHIT SGEALPLDHT LETWIAKEDC PLYNGGNIIL EYLNDEEQFC KNVESYLE
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZFAND1, a member of the ZFAND family of proteins, plays a crucial role in various cellular processes, including protein degradation, apoptosis, and cellular stress responses. It is characterized by the presence of zinc finger motifs, which are fundamental for its interaction with other proteins and regulatory elements. Research has shown that ZFAND1 is implicated in the modulation of the ubiquitin-proteasome system, influencing protein turnover and maintaining cellular homeostasis. Abnormal expression or mutations in ZFAND1 have been associated with multiple diseases, including cancer and neurodegenerative disorders, highlighting its potential as a therapeutic target. Moreover, studies suggest that ZFAND1 may also be involved in immune responses, acting as a regulator of inflammatory pathways. Recent advancements in structural biology have enabled the detailed characterization of ZFAND1, providing insight into its functional mechanisms and interactions within the cell. As researchers continue to unravel the complexities of ZFAND1, it is becoming increasingly evident that understanding its role in cellular dynamics could lead to novel strategies for disease intervention and treatment.
