Analytical Data
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Gene name
PGBD2
- Application
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Alternative Names
PGBD2; PiggyBac transposable element-derived protein 2
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q6P3X8
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Expression Region
1-592 aa
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AA Sequence
MASTSRDVIA GRGIHSKVKS AKLLEVLNAM EEEESNNNRE EIFIAPPDNA AGEFTDEDSG DEDSQRGAHL PGSVLHASVL CEDSGTGEDN DDLELQPAKK RQKAVVKPQR IWTKRDIRPD FGSWTASDPH IEDLKSQELS PVGLFELFFD EGTINFIVNE TNRYAWQKNV NLSLTAQELK CVLGILILSG YISYPRRRMF WETSPDSHHH LVADAIRRDR FELIFSYLHF ADNNELDASD RFAKVRPLII RMNCNFQKHA PLEEFYSFGE SMCEYFGHRG SKQLHRGKPV RLGYKIWCGT TSRGYLVWFE PSQGTLFTKP DRSLDLGGSM VIKFVDALQE RGFLPYHIFF DKVFTSVKLM SILRKKGVKA TGTVREYRTE RCPLKDPKEL KKMKRGSFDY KVDESEEIIV CRWHDSSVVN ICSNAVGIEP VRLTSRHSGA AKTRTQVHQP SLVKLYQEKV GGVGRMDQNI AKYKVKIRGM KWYSSFIGYV IDAALNNAWQ LHRICCQDAQ VDLLAFRRYI ACVYLESNAD TTSQGRRSRR LETESRFDMI GHWIIHQDKR TRCALCHSQT NTRCEKCQKG VHAKCFREYH IR
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Molecular Weight
68.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PGBD2 (Pogo Transposable Element Derived 2) is a member of the PGBD family of proteins initially identified for its transposable element-like characteristics. It has garnered attention due to its potential roles in genome stability, DNA repair, and cancer biology. Recent studies have indicated that PGBD2 may play a crucial role in the repair of double-strand breaks in DNA, an essential process for maintaining genomic integrity. Its expression is often dysregulated in various cancers, suggesting a potential oncogenic role. Furthermore, PGBD2 has been implicated in processes such as chromatin remodeling and cellular differentiation, contributing to its significance in developmental biology. The interest in PGBD2 has prompted researchers to explore recombinant protein production to better understand its structure and function. By expressing PGBD2 as a recombinant protein, researchers aim to elucidate its biochemical properties, interaction partners, and mechanisms of action. This knowledge could pave the way for novel therapeutic strategies targeting PGBD2-related pathways, particularly in cancer treatment. As the versatility of recombinant proteins allows for detailed in vitro studies, the ongoing research on PGBD2 holds promise for advancing our understanding of its biological roles and potential clinical applications.
