Analytical Data
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基因名
CDC37L1
- Application
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别名
CDC37L1；CDC37B；HARC；Hsp90 co-chaperone Cdc37-like 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q7L3B6
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表达区间
1-337aa
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氨基酸序列
MEQPWPPPGP WSLPRAEGEA EEESDFDVFP SSPRCPQLPG GGAQMYSHGI ELACQKQKEF VKSSVACKWN LAEAQQKLGS LALHNSESLD QEHAKAQTAV SELRQREEEW RQKEEALVQR EKMCLWSTDA ISKDVFNKSF INQDKRKDTE DEDKSESFMQ KYEQKIRHFG MLSRWDDSQR FLSDHPYLVC EETAKYLILW CFHLEAEKKG ALMEQIAHQA VVMQFIMEMA KNCNVDPRGC FRLFFQKAKA EEEGYFEAFK NELEAFKSRV RLYSQSQSFQ PMTVQNHVPH SGVGSIGLLE SLPQNPDYLQ YSISTALCSL NSVVHKEDDE PKMMDTV
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分子量
38.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CDC37L1, a member of the CDC37 family, is a co-chaperone that plays a critical role in the maturation and stabilization of various protein kinases and other client proteins. Due to its involvement in essential cellular processes, including cell cycle regulation, signal transduction, and stress response, CDC37L1 has garnered attention in cancer research and other diseases characterized by dysregulated protein homeostasis. Overexpression or aberrant functioning of CDC37L1 has been linked to various malignancies, suggesting that targeting this protein could offer new therapeutic avenues. Additionally, the study of CDC37L1 recombinant proteins allows researchers to elucidate its functional mechanisms, interactions with client proteins, and potential as a biomarker or therapeutic target. Understanding the structural and functional properties of CDC37L1 through recombinant protein techniques can provide insights into its role in cellular physiology and pathology, paving the way for innovative strategies in drug development and disease management.
