Cat: PA2000-1625

Recombinant Human CDC37L1 Protein,His

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Analytical Data

  • Gene name

    CDC37L1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    CDC37L1;CDC37B;HARC;Hsp90 co-chaperone Cdc37-like 1

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q7L3B6

  • Expression Region

    1-337aa

  • AA Sequence

    MEQPWPPPGP WSLPRAEGEA EEESDFDVFP SSPRCPQLPG GGAQMYSHGI ELACQKQKEF VKSSVACKWN LAEAQQKLGS LALHNSESLD QEHAKAQTAV SELRQREEEW RQKEEALVQR EKMCLWSTDA ISKDVFNKSF INQDKRKDTE DEDKSESFMQ KYEQKIRHFG MLSRWDDSQR FLSDHPYLVC EETAKYLILW CFHLEAEKKG ALMEQIAHQA VVMQFIMEMA KNCNVDPRGC FRLFFQKAKA EEEGYFEAFK NELEAFKSRV RLYSQSQSFQ PMTVQNHVPH SGVGSIGLLE SLPQNPDYLQ YSISTALCSL NSVVHKEDDE PKMMDTV

  • Molecular Weight

    38.8 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

CDC37L1, a member of the CDC37 family, is a co-chaperone that plays a critical role in the maturation and stabilization of various protein kinases and other client proteins. Due to its involvement in essential cellular processes, including cell cycle regulation, signal transduction, and stress response, CDC37L1 has garnered attention in cancer research and other diseases characterized by dysregulated protein homeostasis. Overexpression or aberrant functioning of CDC37L1 has been linked to various malignancies, suggesting that targeting this protein could offer new therapeutic avenues. Additionally, the study of CDC37L1 recombinant proteins allows researchers to elucidate its functional mechanisms, interactions with client proteins, and potential as a biomarker or therapeutic target. Understanding the structural and functional properties of CDC37L1 through recombinant protein techniques can provide insights into its role in cellular physiology and pathology, paving the way for innovative strategies in drug development and disease management.

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