Cat: PAX2000-10226

Recombinant Human PDZD7 Protein,His

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Analytical Data

  • Gene name

    PDZD7

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    9130207N01; EG435601; OTTMUSP00000044304; OTTMUSP00000044305; PDZ domain containing 7; PDZ domain-containing protein 7; PDZD7; PDZD7_HUMAN; PDZK7; RP11-108L7.9

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    Q9H5P4

  • Expression Region

    1-517 aa

  • AA Sequence

    MAQGFAVGFD PLGLGDLSSG SLSSLSSRGH LGSDSGSTAT RYLLRKQQRL LNGPPRGIRA SSPMGRVILI NSPIEANSDE SDIIHSVRVE KSPAGRLGFS VRGGSEHGLG IFVSKVEEGS SAERAGLCVG DKITEVNGLS LESTTMGSAV KVLTSSSRLH MMVRRMGRVP GIKFSKEKTT WVDVVNRRLV VEKCGSTPSD TSSEDGVRRI VHLYTTSDDF CLGFNIRGGK EFGLGIYVSK VDHGGLAEEN GIKVGDQVLA ANGVRFDDIS HSQAVEVLKG QTHIMLTIKE TGRYPAYKEM VSEYCWLDRL SNGVLQQLSP ASESSSSVSS CASSAPYSSG SLPSDRMDIC LGQEEPGSRG PGWGRADTAM QTEPDAGGRV ETWCSVRPTV ILRDTAIRSD GPHPGRRLDS ALSESPKTAL LLALSRPRPP ITRSQSYLTL WEEKQQRKKE KSGSPGEKGA LQRSKTLMNL FFKGGRQGRL ARDGRREAWT LDSGSLAKTY PRLDIEKEMG VSPCCPG

  • Molecular Weight

    111.7 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

PDZD7, a member of the PDZ domain-containing protein family, plays a critical role in various cellular processes, including cell adhesion, signaling, and synaptic formation. Recent research has highlighted its involvement in crucial biological functions, particularly in the context of neurodevelopmental disorders and certain types of cancer. The PDZ domain is known for its capability to bind with C-terminal residues of other proteins, which facilitates the formation of protein complexes that are essential for cellular signaling pathways. Recombinant PDZD7 protein has emerged as a valuable tool in understanding its molecular mechanisms and interactions. Generating PDZD7 in a recombinant form allows for detailed biochemical assays and structural studies, aiding in the elucidation of its function in health and disease. Investigating PDZD7 through recombinant technology not only enhances our understanding of its role in normal physiology but also offers insights into potential therapeutic targets for related pathologies. As ongoing studies focus on its protein-protein interactions and downstream signaling pathways, recombinant PDZD7 continues to be pivotal in unraveling the complexities of cellular communication and its implications in human health.

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