Analytical Data
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Gene name
ATAD1
- Application
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Alternative Names
4921525H23Rik; AAA+ ATPase Thorase; Ab2-088; AFDC1; Atad1; ATAD1_HUMAN
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q8NBU5
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Expression Region
1-361aa
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AA Sequence
MVHAEAFSRP LSRNEVVGLI FRLTIFGAVT YFTIKWMVDA IDPTRKQKVE AQKQAEKLMK QIGVKNVKLS EYEMSIAAHL VDPLNMHVTW SDIAGLDDVI TDLKDTVILP IKKKHLFENS RLLQPPKGVL LYGPPGCGKT LIAKATAKEA GCRFINLQPS TLTDKWYGES QKLAAAVFSL AIKLQPSIIF IDEIDSFLRN RSSSDHEATA MMKAQFMSLW DGLDTDHSCQ VIVMGATNRP QDLDSAIMRR MPTRFHINQP ALKQREAILK LILKNENVDR HVDLLEVAQE TDGFSGSDLK EMCRDAALLC VREYVNSTSE ESHDEDEIRP VQQQDLHRAI EKMKKSKDAA FQNVLTHVCL D
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Molecular Weight
40 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ATAD1 (ATPase family AAA domain-containing protein 1) is a vital protein implicated in various cellular processes, including protein sorting, mitochondrial function, and the regulation of proteostasis. Understanding the structure and function of ATAD1 is crucial as it plays a role in cellular response to stress and can influence the development of several diseases, including neurodegenerative disorders and cancers. Researchers have increasingly focused on the recombinant expression of ATAD1 to investigate its biochemical properties, interaction networks, and potential therapeutic targets. The ability to produce ATAD1 in a controlled environment allows for detailed study of its ATPase activity and mechanistic insights into how it orchestrates complex cellular functions. Furthermore, studies have suggested that dysregulation of ATAD1 may lead to pathophysiological conditions, emphasizing the importance of its functional analysis. As a result, ongoing research aims to elucidate the roles of ATAD1 in cellular homeostasis, the molecular mechanisms underlying its activity, and its potential involvement in disease progression, paving the way for novel therapeutic strategies targeting ATAD1-related pathways.
