Analytical Data
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基因名
PCDH11X
- Application
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别名
PC11X_HUMAN; PCDH-X; PCDH11; PCDH11X; PCDHX; PPP1R119; Protein phosphatase 1 regulatory subunit 119; Protocadherin 11X; Protocadherin on the X chromosome; Protocadherin-11; Protocadherin-11 X-linked; Protocadherin-S
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BZA7
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表达区间
57-165 aa
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氨基酸序列
EKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDIN
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分子量
37.73 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PCDH11X (Protocadherin 11 X-linked) is a member of the protocadherin superfamily, which plays a crucial role in cell signaling and adhesion, particularly in neural tissues. Research into PCDH11X has gained traction due to its potential implications in neurological disorders, such as autism spectrum disorders and schizophrenia, as genetic studies have identified associations between PCDH11X mutations and these conditions. The gene is located on the X chromosome, making it particularly interesting for understanding sex-linked differences in neurodevelopmental traits. Recent advancements in recombinant protein technology have enabled the production of PCDH11X proteins, facilitating studies on its structural properties and functional mechanisms. Investigating PCDH11X through recombinant approaches allows researchers to explore its interactions with other cellular components, elucidate its role in synaptogenesis, and assess its potential as a therapeutic target. The development of PCDH11X recombinant proteins not only aids in advancing our knowledge of this protocadherin but also contributes to broader efforts in identifying molecular pathways involved in neurodevelopmental disorders. As the field moves forward, understanding the biology of PCDH11X could pave the way for novel diagnostic and therapeutic strategies to mitigate the impact of related diseases.
