Analytical Data
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Gene name
ACSM3
- Application
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Alternative Names
ACSM3；SAH；Acyl-coenzyme A synthetase ACSM3. mitochondrial
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q53FZ2
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Expression Region
28-586aa
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AA Sequence
LHK DNRTATPQNF SNYESMKQDF KLGIPEYFNF AKDVLDQWTD KEKAGKKPSN PAFWWINRNG EEMRWSFEEL GSLSRKFANI LSEACSLQRG DRVILILPRV PEWWLANVAC LRTGTVLIPG TTQLTQKDIL YRLQSSKANC IITNDVLAPA VDAVASKCEN LHSKLIVSEN SREGWGNLKE LMKHASDSHT CVKTKHNEIM AIFFTSGTSG YPKMTAHTHS SFGLGLSVNG RFWLDLTPSD VMWNTSDTGW AKSAWSSVFS PWIQGACVFT HHLPRFEPTS ILQTLSKYPI TVFCSAPTVY RMLVQNDITS YKFKSLKHCV SAGEPITPDV TEKWRNKTGL DIYEGYGQTE TVLICGNFKG MKIKPGSMGK PSPAFDVKIV DVNGNVLPPG QEGDIGIQVL PNRPFGLFTH YVDNPSKTAS TLRGNFYITG DRGYMDKDGY FWFVARADDV ILSSGYRIGP FEVENALNEH PSVAESAVVS SPDPIRGEVV KAFVVLNPDY KSHDQEQLIK EIQEHVKKTT APYKYPRKVE FIQELPKTIS GKTKRNELRK KEWKTI
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Molecular Weight
66 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The study of the recombinant protein ACSM3 (Acyl-CoA Synthetase Medium Chain Family Member 3) is significant due to its potential implications in metabolic processes and disease states. ACSM3 is an enzyme involved in the activation of medium-chain fatty acids by converting them into acyl-CoA, which is critical for various cellular functions including energy production and lipid metabolism. Research has shown that alterations in the expression or activity of ACSM3 may be linked to metabolic disorders such as obesity, type 2 diabetes, and fatty liver disease. Furthermore, understanding the functional properties of ACSM3 could provide insights into the regulation of lipid metabolism at a molecular level. The production of recombinant ACSM3 allows for in-depth biochemical studies and the characterization of its enzymatic activities, substrate specificity, and interactions with other metabolic pathways. This recombinant approach also facilitates the exploration of its role in different physiological and pathological contexts. As current therapeutic strategies for metabolic diseases are often limited, further elucidation of ACSM3's role could pave the way for novel interventions targeting lipid metabolism, ultimately contributing to the development of effective treatments for related health conditions. Thus, ACSM3 serves as a crucial target for research aimed at enhancing our understanding of metabolic regulation and potential therapeutic avenues.
