Analytical Data
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基因名
TSPAN7
- Application
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别名
TSPAN7;A15;Tetraspanin-7
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P41732
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表达区间
113-213aa
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氨基酸序列
ADPRHEIKDT FLRTYTDAMQ TYNGNDERSR AVDHVQRSLS CCGVQNYTNW STSPYFLEHG IPPSCCMNET DCNPQDLHNL TVAATKVNQK GCYDLVTSFM ETNMHHHHHH
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分子量
13 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TSPAN7, or Tetraspanin 7, is a member of the tetraspanin family of proteins, which are known for their role in organizing membrane microdomains and facilitating cell-cell interactions. Research into TSPAN7 has gained significant attention due to its implications in various neurological disorders, particularly in relation to synaptic function and plasticity. Studies have demonstrated that TSPAN7 plays a crucial role in the development and maintenance of neuronal connections, influencing processes such as neurotransmitter release and receptor trafficking. Genetic mutations in the TSPAN7 gene have been associated with autism spectrum disorders and intellectual disabilities, highlighting its importance in neurodevelopment. Furthermore, TSPAN7 is implicated in several other cellular processes, including cell migration and signaling pathways. Given the protein's multifaceted roles, the production of recombinant TSPAN7 has become essential for investigating its molecular mechanisms and interactions. Recombinant TSPAN7 proteins are used in various experimental settings to elucidate their structural characteristics and functional properties, enabling researchers to better understand its contribution to neurological health and disease. Overall, the ongoing research on TSPAN7 not only sheds light on fundamental biological processes but also offers potential avenues for therapeutic interventions in neurodevelopmental disorders.












