Analytical Data
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Gene name
TSC22D3
- Application
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Alternative Names
TSC22D3；Nuclear factor NF-kappa-B p105 subunit
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q99576
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Expression Region
1-134aa
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AA Sequence
MNTEMYQTPM EVAVYQLHNF SISFFSSLLG GDVVSVKLDN SASGASVVAI DNKIEQAMDL VKNHLMYAVR EEVEILKEQI RELVEKNSQL ERENTLLKTL ASPEQLEKFQ SCLSPEEPAP ESPQVPEAPG GSAV
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The TSC22D3 protein, a member of the TSC22 domain-containing family, has gained attention in the fields of immunology and cellular biology due to its role in various physiological and pathological processes. It is particularly noted for its involvement in the regulation of inflammation and immune responses. Research indicates that TSC22D3 plays a crucial role in mediating the effects of cytokines and growth factors, making it a significant player in tissue repair and regeneration. Dysregulation of TSC22D3 has been implicated in several diseases, including autoimmune disorders and cancer, highlighting its potential as a therapeutic target. Studies have shown that TSC22D3 can modulate gene expression and influence cell signaling pathways, suggesting its multifaceted role in cellular homeostasis and response to stress. As researchers continue to explore the mechanisms underlying TSC22D3 function, the development of recombinant TSC22D3 protein has become pivotal for elucidating its biological activity and potential applications in medicine. This recombinant protein allows for detailed in vitro and in vivo studies, providing insights into its interactions and effects on different cell types and conditions. Understanding the biochemical properties and signaling pathways associated with TSC22D3 may pave the way for novel therapeutic strategies aimed at modulating immune responses or correcting dysfunctional signaling in various diseases. Overall, the investigation of TSC22D3 and its recombinant form represents a promising avenue in contemporary biomedical research, with the potential to unveil new insights into immune regulation and disease treatment.
