Analytical Data
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基因名
TSC22D3
- Application
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别名
TSC22D3；Nuclear factor NF-kappa-B p105 subunit
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q99576
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表达区间
1-134aa
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氨基酸序列
MNTEMYQTPM EVAVYQLHNF SISFFSSLLG GDVVSVKLDN SASGASVVAI DNKIEQAMDL VKNHLMYAVR EEVEILKEQI RELVEKNSQL ERENTLLKTL ASPEQLEKFQ SCLSPEEPAP ESPQVPEAPG GSAV
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The TSC22D3 protein, a member of the TSC22 domain-containing family, has gained attention in the fields of immunology and cellular biology due to its role in various physiological and pathological processes. It is particularly noted for its involvement in the regulation of inflammation and immune responses. Research indicates that TSC22D3 plays a crucial role in mediating the effects of cytokines and growth factors, making it a significant player in tissue repair and regeneration. Dysregulation of TSC22D3 has been implicated in several diseases, including autoimmune disorders and cancer, highlighting its potential as a therapeutic target. Studies have shown that TSC22D3 can modulate gene expression and influence cell signaling pathways, suggesting its multifaceted role in cellular homeostasis and response to stress. As researchers continue to explore the mechanisms underlying TSC22D3 function, the development of recombinant TSC22D3 protein has become pivotal for elucidating its biological activity and potential applications in medicine. This recombinant protein allows for detailed in vitro and in vivo studies, providing insights into its interactions and effects on different cell types and conditions. Understanding the biochemical properties and signaling pathways associated with TSC22D3 may pave the way for novel therapeutic strategies aimed at modulating immune responses or correcting dysfunctional signaling in various diseases. Overall, the investigation of TSC22D3 and its recombinant form represents a promising avenue in contemporary biomedical research, with the potential to unveil new insights into immune regulation and disease treatment.
